Using LED light to treat skin discoloration

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of 830 nm and 590 nm LED phototherapies in preventing and treating post-inflammatory erythema (PIE) and post-inflammatory hyperpigmentation (PIH). Healthy participants aged 20-65 with specific skin types will undergo LED treatments after inducing skin discoloration. The study will measure changes in skin conditions using various indices and photography over a 10-day follow-up period. The goal is to gather evidence on the efficacy of LED light therapy for these skin conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Healthy Asians;
2. 20-65 years old;
3. Fitzpatrick classification III-IV;
4. Sign the informed consent form.

Exclusion Criteria:

1. Have abnormal skin manifestations, such as pigment diseases, photosensitivity diseases and other allergic diseases;
2. Those with a history of abnormal systemic diseases, such as heart disease, liver disease, kidney disease, tumors, and mental illness;
3. Women who are preparing for pregnancy, pregnant or breastfeeding;
4. Have used photosensitizing drugs within two weeks before inclusion in this study;
5. Topical or systemic drugs may be used during this study;
6. bad habits, such as smoking, drinking, etc.;
7. Volunteers who have recently participated in other clinical trials;

Where it's running

• Huashan Hospital
  Shanghai, China Recruiting

Study contacts

• Principal investigator: Leihong Xiang, professor — Huashan Hospital
• Study coordinator: Yanjun Dan
• Email: danyanjun@126.com
• Phone: +86 159 0194 0897

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Cosmetic gel for facial hyperpigmentation in women

  This study tests a depigmenting gel to see if it improves facial dark spots in 40 women aged 30–60 over 90 days.

  Recruiting Brainfarma Industria Química e Farmacêutica S/A · Osasco, São Paulo · NCT07769268

• Lip product with Caulerpa lentillifera extract to reduce dark lips

  We will test if a lip product containing Caulerpa lentillifera extract can reduce darkened lips in Thai adults aged 18–60 who are concerned about lip pigmentation.

  Recruiting Chulalongkorn University · Bangkok · NCT07067879

• Using a hybrid laser to treat acne scars in people with darker skin

  This study is testing a new type of laser treatment for acne scars to see if it works well and is safe for people with darker skin.

  Recruiting Montefiore Medical Center · Elmsford, New York · NCT05362929

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.