Using laser treatment to prevent tooth decay in children's molars
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
NA · Alexandria University · NCT06826456
This study is testing whether a special laser treatment can help prevent tooth decay in the back teeth of children aged 6 to 12 compared to fluoride varnish.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 6 Years to 12 Years |
| Sex | All |
| Sponsor | Alexandria University (other) |
| Locations | 1 site (Alexandria) |
| Trial ID | NCT06826456 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of Er,Cr:YSGG sub-ablative laser irradiation in preventing caries in the occlusal fissures of permanent molars in children aged 6-12. It is a split-mouth randomized controlled trial involving sixty patients, where one set of molars will receive laser treatment while the other set will be treated with fluoride varnish. The study will assess changes in caries resistance using DIAGNOdent readings and ICDAS-II scores over a 12-month follow-up period.
Who should consider this trial
Good fit: Ideal candidates are children aged 6-12 with at least two bilateral fully erupted first permanent molars that have non-cavitated occlusal surfaces.
Not a fit: Patients with systemic diseases, enamel defects, or recent fluoride treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a novel, effective method for preventing tooth decay in children's molars.
How similar studies have performed: While the use of lasers in dental treatments is gaining interest, this specific approach to caries prevention is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants of age 6-12 years old * Patients ranking definitely positive or positive on Frankl behavior rating scale * Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)/ severity scores 0, 1 or 2 * Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement * Patients whom their parents are willing to comply with all study procedures and protocols and will be given an informed consent to participate Exclusion Criteria: * Patients with any known medical history of systemic diseases * Patients having first permanent molar with hypoplastic or hypocalcified enamel * Patients using medications that may affect the oral flora or salivary flow * Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study. * Patients showing evidence of poor oral hygiene according to Silness and Löe plaque index
Where this trial is running
Alexandria
- Alexandria University — Alexandria, Egypt (RECRUITING)
Study contacts
- Study coordinator: Hussein Ezz Eldin
- Email: hussein.ezz@hotmail.com
- Phone: +20 10 92403402
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Caries,Dental, Er,Cr:YSGG, laser, DIAGNOdentTM, acid resistance