Using laser treatment to prevent tooth decay in children's molars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of Er,Cr:YSGG sub-ablative laser irradiation in preventing caries in the occlusal fissures of permanent molars in children aged 6-12. It is a split-mouth randomized controlled trial involving sixty patients, where one set of molars will receive laser treatment while the other set will be treated with fluoride varnish. The study will assess changes in caries resistance using DIAGNOdent readings and ICDAS-II scores over a 12-month follow-up period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants of age 6-12 years old
* Patients ranking definitely positive or positive on Frankl behavior rating scale
* Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)/ severity scores 0, 1 or 2
* Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement
* Patients whom their parents are willing to comply with all study procedures and protocols and will be given an informed consent to participate

Exclusion Criteria:

* Patients with any known medical history of systemic diseases
* Patients having first permanent molar with hypoplastic or hypocalcified enamel
* Patients using medications that may affect the oral flora or salivary flow
* Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study.
* Patients showing evidence of poor oral hygiene according to Silness and Löe plaque index

Where it's running

• Alexandria University
  Alexandria, Egypt Recruiting

Study contacts

• Study coordinator: Hussein Ezz Eldin
• Email: hussein.ezz@hotmail.com
• Phone: +20 10 92403402

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.