Using laser technology to detect rheumatoid arthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This feasibility study aims to adapt photoacoustic tomography (PAT), a novel noninvasive laser-based imaging technology, for detecting chronic rheumatoid arthritis in humans. By combining the benefits of light and ultrasound scanning, PAT seeks to provide high sensitivity and spatial resolution in imaging peripheral joints affected by inflammatory arthritis. The study will assess the effectiveness of PAT in early detection and understanding the pathophysiology of rheumatoid arthritis, potentially aiding in therapeutic decisions and the evaluation of new treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men and women 18 years of age or older can participate in this study.
* Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study.
* Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis.

Exclusion Criteria:

* Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
* Pregnant patients.
* Patients who is claustrophobic.
* Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc.
* Patients with shock hypotension or unstable low blood pressure.
* Patients with Rhabdomyolysis.
* Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures).

Where it's running

• Universtity of Michigan Health System
  Ann Arbor, Michigan, United States Recruiting

Study contacts

• Principal investigator: Xueding Wang, Ph.D — University of Michigan
• Study coordinator: Safa Mohamed
• Email: safam@med.umich.edu
• Phone: 734 615-1646

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.