Using Ketamine and Tramadol to Prevent Shivering After Spinal Anesthesia
Frequency of Shivering Among Patient Treaed With IV Tramadol Versus Iv Ketamine in Prevention of Post Spinal Anesthesia Undergoing Cesarean Section: Rendomiced Control Trial
PHASE3 · Liaquat National Hospital & Medical College · NCT06722742
This study is testing if giving ketamine or tramadol can help prevent shivering in women after they have a cesarean section.
Quick facts
| Phase | PHASE3 |
|---|---|
| Study type | Interventional |
| Enrollment | 250 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | Liaquat National Hospital & Medical College (other) |
| Locations | 3 sites (Karachi, Sindh and 2 other locations) |
| Trial ID | NCT06722742 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of ketamine and tramadol in preventing post-spinal anesthesia shivering in patients undergoing elective cesarean sections. The study aims to reduce discomfort and anxiety associated with shivering by utilizing these medications, which work by blocking nerve signals and affecting temperature regulation in the brain. Participants will receive either ketamine or tramadol to assess their impact on shivering response and overall patient satisfaction during recovery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 18 to 40 years undergoing elective cesarean sections with an ASA classification of 1 or 2.
Not a fit: Patients requiring general anesthesia for their cesarean section or those with a history of cardiovascular disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance patient comfort and satisfaction during recovery from spinal anesthesia.
How similar studies have performed: While the use of ketamine and tramadol for shivering prevention is a novel approach, similar studies have shown promising results in managing post-anesthesia complications.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pateint for elective cesarean section * Age 18 to 40 years * ASA 1 and 2 Exclusion Criteria: * ASA 2 and 3 * Cesarean section requiring general anesthesia * Hypersensitivity to Ketamine, Tramadol and Opiods * History of cardiovascular disease
Where this trial is running
Karachi, Sindh and 2 other locations
- Liaquat National Hospital and Medical College — Karachi, Sindh, Pakistan (RECRUITING)
- Liaquat National Hospital and Medical College — Karachi, Sindh, Pakistan (RECRUITING)
- Liaquat National Hospital and Medical College — Karachi, Sindh, Pakistan (RECRUITING)
Study contacts
- Principal investigator: Nazish Dr Nazish Kanwal — Liaquat national hospital and medical college
- Study coordinator: Nazish Dr Nazish Kanwal
- Email: Naz98783@gmail.com
- Phone: 03292163092
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Shivering, Spinal Anesthesia, shivering, Spinal anesthesia, Ketamine, Tramadol and Metclopromide