Using Ketamine and Tramadol to Prevent Shivering After Spinal Anesthesia
Official title: Frequency of Shivering Among Patient Treaed With IV Tramadol Versus Iv Ketamine in Prevention of Post Spinal Anesthesia Undergoing Cesarean Section: Rendomiced Control Trial
Run by Liaquat National Hospital & Medical College · NCT06722742 · Data updated 2026-11-12
This study is testing if giving ketamine or tramadol can help prevent shivering in women after they have a cesarean section.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 250 (estimated) |
| Sponsor | Liaquat National Hospital & Medical College Academic / other |
| Locations | 3 sites (Karachi, Sindh and 2 other locations) |
| Status | Recruiting |
| Started | September 30, 2024 |
| Main results expected | December 30, 2024 |
| Study ends | January 30, 2025 |
| Registry record updated | December 9, 2024 |
| Trial ID | NCT06722742 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients aged 18 to 40 years undergoing elective cesarean sections with an ASA classification of 1 or 2.
✕Probably not a fit
Patients requiring general anesthesia for their cesarean section or those with a history of cardiovascular disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of ketamine and tramadol in preventing post-spinal anesthesia shivering in patients undergoing elective cesarean sections. The study aims to reduce discomfort and anxiety associated with shivering by utilizing these medications, which work by blocking nerve signals and affecting temperature regulation in the brain. Participants will receive either ketamine or tramadol to assess their impact on shivering response and overall patient satisfaction during recovery.
Why it matters
Potential benefit: If successful, this approach could significantly enhance patient comfort and satisfaction during recovery from spinal anesthesia.
How similar studies have gone: While the use of ketamine and tramadol for shivering prevention is a novel approach, similar studies have shown promising results in managing post-anesthesia complications.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pateint for elective cesarean section * Age 18 to 40 years * ASA 1 and 2 Exclusion Criteria: * ASA 2 and 3 * Cesarean section requiring general anesthesia * Hypersensitivity to Ketamine, Tramadol and Opiods * History of cardiovascular disease
Where it's running
-
Liaquat National Hospital and Medical College
Karachi, Sindh, Pakistan Recruiting -
Liaquat National Hospital and Medical College
Karachi, Sindh, Pakistan Recruiting -
Liaquat National Hospital and Medical College
Karachi, Sindh, Pakistan Recruiting
Study contacts
- Principal investigator: Nazish Dr Nazish Kanwal — Liaquat national hospital and medical college
- Study coordinator: Nazish Dr Nazish Kanwal
- Email: Naz98783@gmail.com
- Phone: 03292163092
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.