Using kefir mouthwash to improve oral health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research evaluates the effectiveness of kefir mouthwash in enhancing oral health by focusing on key indicators such as gingival inflammation, plaque development, and halitosis. Conducted over 28 days, the study involves 60 healthy adults aged 18 to 28 with moderate gingivitis, who will be randomly assigned to use either kefir mouthwash or chlorhexidine as a control. Clinical parameters will be measured at baseline, 14 days, and 28 days, utilizing a triple-blind design to minimize bias. The study aims to provide a natural alternative to conventional mouthwashes that often have adverse effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age range 18-28 years.
* Systemically healthy people without a history of chronic illness.
* Those suffering with moderate gingivitis.
* Not using any antibiotics over three months

Exclusion Criteria:

* History of systemic diseases.
* Pregnant, lactating females.
* History of antibiotic therapy in the past 3 months.
* History of oral prophylaxis within the last 6 months prior to the study as this can confound the results, making it difficult to determine the real effect of the mouthwash.
* Subjects with mouth breathing habits.
* Subjects with orthodontic and prosthodontic appliances.
* Subjects with deleterious habits such as smoking, because it may affect oral health status, causing periodontal disease, altered oral microbiota, and impaired healing. This can confound the study results, making it difficult to observe the mouthwash effect .
* Failure to follow the prescription regimen.
* Failure to follow the research protocol.

Where it's running

• Al-Mustansiriyah University/College of Dentistry
  Baghdad, Iraq Recruiting

Study contacts

• Principal investigator: Zahra H Al-Tamimi, MS student — Department of prevention, College of dentistry , University of Mustansiriyah
• Study coordinator: Zahra H Al-Tamimi, MS student
• Email: Zahar94@uomustansiriyah.edu.iq
• Phone: 009647806462936

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.