Using kefir mouthwash to improve oral health
Role of Kefir Mouth Wash in Oral Health Status Amelioration: An in Vivo Study
This study is testing if using kefir mouthwash can help young adults with gum inflammation improve their oral health compared to a standard mouthwash.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 28 Years |
| Sex | All |
| Sponsor | Al-Mustansiriyah University Academic / other |
| Locations | 1 site (Baghdad) |
| Trial ID | NCT06900881 on ClinicalTrials.gov |
What this trial studies
This research evaluates the effectiveness of kefir mouthwash in enhancing oral health by focusing on key indicators such as gingival inflammation, plaque development, and halitosis. Conducted over 28 days, the study involves 60 healthy adults aged 18 to 28 with moderate gingivitis, who will be randomly assigned to use either kefir mouthwash or chlorhexidine as a control. Clinical parameters will be measured at baseline, 14 days, and 28 days, utilizing a triple-blind design to minimize bias. The study aims to provide a natural alternative to conventional mouthwashes that often have adverse effects.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy adults aged 18 to 28 with moderate gingivitis.
Not a fit: Patients with systemic diseases, pregnant or lactating females, or those with certain oral health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer a natural and effective mouthwash alternative that improves oral health without the negative side effects associated with traditional products.
How similar studies have performed: While the use of kefir in oral health is gaining interest, this specific approach is relatively novel and has not been extensively tested in previous studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age range 18-28 years. * Systemically healthy people without a history of chronic illness. * Those suffering with moderate gingivitis. * Not using any antibiotics over three months Exclusion Criteria: * History of systemic diseases. * Pregnant, lactating females. * History of antibiotic therapy in the past 3 months. * History of oral prophylaxis within the last 6 months prior to the study as this can confound the results, making it difficult to determine the real effect of the mouthwash. * Subjects with mouth breathing habits. * Subjects with orthodontic and prosthodontic appliances. * Subjects with deleterious habits such as smoking, because it may affect oral health status, causing periodontal disease, altered oral microbiota, and impaired healing. This can confound the study results, making it difficult to observe the mouthwash effect . * Failure to follow the prescription regimen. * Failure to follow the research protocol.
Where this trial is running
Baghdad
- Al-Mustansiriyah University/College of Dentistry — Baghdad, Iraq (Recruiting)
Study contacts
- Principal investigator: Zahra H Al-Tamimi, MS student — Department of prevention, College of dentistry , University of Mustansiriyah
- Study coordinator: Zahra H Al-Tamimi, MS student
- Email: Zahar94@uomustansiriyah.edu.iq
- Phone: 009647806462936
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.