Using interferential current with exercise for knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of incorporating interferential current (IC) into a therapeutic exercise program for individuals suffering from knee osteoarthritis (KOA). Participants aged 40 to 75 with unilateral KOA and specific pain criteria will engage in a program that combines therapeutic exercise with either active or placebo IC. The study aims to assess improvements in pain intensity, functionality, self-efficacy, and overall perceived effects of the treatment. By comparing the outcomes of the two groups, the research seeks to determine the efficacy of IC in enhancing the benefits of exercise for KOA patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* both sexes
* between 40 years old and 75 years old
* with a clinical diagnosis of unilateral KOA
* Who has had knee pain for more than 3 months
* With a minimum score of 3 points on the numerical pain scale
* Morning stiffness for less than 30 minutes
* Crepitus
* Bone tenderness and absence of palpable heat

Exclusion Criteria:

* Hip OA
* Severe osteoporosis
* Fibromyalgia
* Clinical history of tumors or cancer
* Active inflammatory joint diseases (rheumatoid arthritis, gout)
* Undergoing any joint replacement in the lower extremity
* Neurological diseases (Parkinson's disease, stroke
* Multiple sclerosis
* muscular dystrophies
* Diseases involving motor neurons
* Alzheimer's disease
* Infected wounds or osteomyelitis in the knee region
* Deep vein thrombosis or thrombophlebitis
* Sensory alteration in the lower limbs
* Cognitive and cardiopulmonary impairment that may prevent or limit the execution of exercises
* Use of a walking assistance device
* History of recent knee trauma
* Having undergone any form of treatment involving physical therapy
* intra-articular corticosteroids
* anti-inflammatory drugs
* opioid medication or chondroprotective in the six months before the start of the interventions

Where it's running

• University of Nove de Julho
  São Paulo, Brazil Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• SVF cellular mix, secretome, and knee response in osteoarthritis

  This study tests the cellular composition and secretome of research-only adipose-derived SVF in adults with knee OA who are already planned to receive an autologous SVF injection as part of their care.

  Recruiting Yonsei University · Seoul · NCT07898501

• Effect of a Resistance Exercise Program on IGF-1 Levels in Knee Osteoarthritis

  A structured 8-week resistance exercise program is being tested to see if it changes blood IGF-1 levels and improves knee OA symptoms in adults with knee OA and metabolic traits.

  Recruiting Sisli Hamidiye Etfal Training and Research Hospital · Istanbul, Istanbul · NCT07890155

• 2-mm subchondral drilling vs sequential 4-mm and 2-mm drilling during CARTISTEM implantation for knee cartilage defects

  This study tests whether drilling the knee with a 2-mm drill alone works as well as sequential 4-mm then 2-mm drilling when combined with CARTISTEM treatment for medial knee cartilage defects.

  Recruiting Yonsei University · Seoul · NCT07881445

• Undenatured Type II Collagen for Knee Osteoarthritis Pain (Three-Arm Trial)

  This study tests whether taking undenatured type II collagen capsules once daily for 4 months can reduce knee pain in adults with knee osteoarthritis, compared with two collagen formulations and a placebo.

  Recruiting Universidad Católica San Antonio de Murcia · Murcia, Murcia · NCT07870967

• Serum Fetuin‑A and COMP levels in knee osteoarthritis

  This study tests whether levels of Fetuin‑A and COMP in the blood relate to how severe knee osteoarthritis is in patients compared with healthy volunteers.

  Recruiting Antalya Training and Research Hospital · Antalya · NCT07706569

• Pain relief for knee osteoarthritis: a 2nd phase study of LY4065967 vs placebo

  Researchers are testing whether LY4065967 can help reduce knee pain from osteoarthritis in adults, compared with placebo.

  Recruiting at 36 sites Phase 2 Eli Lilly and Company · Birmingham, Alabama and 35 other locations · NCT07641517

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.