Using infrared imaging to assess spinal cord stimulation effects in CRPS patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of Forward Looking InfraRed (FLIR) imaging in monitoring sympathetic activity in patients with Complex Regional Pain Syndrome (CRPS) before and after spinal cord stimulation (SCS). It will assess whether SCS enhances sympatholytic activity and how this correlates with various outcome measures, including pain levels and quality of life. Participants will have thermal images of their feet taken and will complete questionnaires regarding their symptoms and functional capacity. The study seeks to provide insights into the relationship between SCS and sympathetic dysfunction in CRPS patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The patient is between 18 and 85 years old
* Providing CRPS diagnostic criteria by using the Budapest Clinical Diagnostic Criteria.
* CRPS affecting unilateral lower extremity
* The patient has had pain and other symptoms for more than 3 months
* Not responding to conventional medical treatments and multidisciplinary approach
* High NRS detection in pain assessment despite appropriate treatment (NRS= and \> 6/10).
* Pain causing a limitation in the patient's functional capacity despite appropriate treatment.

Exclusion Criteria:

* Patients with suspected disc herniation, spinal stenosis, myelopathy, and suspected radiculopathy in detailed examinations and examinations (MRI, CT).
* Systemic or local infection
* Coagulation disorders
* History of allergy to contrast material
* Malignancy
* Pregnancy
* Uncontrollable medical and psychiatric condition
* The patients diagnosed with dysautonomia, sympathetic dysfunction other than CRPS (such as Raynaud disease or Buerger disease), sweating disorders other than CRPS (such as acquired idiopathic generalized anhidrosis), and patients

Where it's running

• Hospital for Special Surgery
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Semih Gungor, MD — Hospital for Special Surgery, New York
• Study coordinator: Pa Thor, PhD
• Email: thorp@hss.edu
• Phone: 646-797-8535

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.