Using indocyanine green to improve lymph node detection in breast cancer patients

INDOCYANINE GREEN for SELECTIVE SENTINELLA AXILLARY LYMPH NODE BIOPSY in PATIENTS with BREAST CANCER

Observational Omphis Foundation · NCT06378944

This study is testing if using a special dye called indocyanine green along with the usual method can help doctors find lymph nodes better in breast cancer patients.

Quick facts

Study typeObservational
Enrollment15000 (estimated)
Ages18 Years to 120 Years
SexAll
SponsorOmphis Foundation Academic / other
Locations1 site (Cerdanyola del Vallès, Barcelona)
Trial IDNCT06378944 on ClinicalTrials.gov

What this trial studies

This observational study aims to enhance the detection of sentinel lymph nodes in breast cancer patients by using indocyanine green in addition to the standard technetium 99 method. During the procedure, 1 ml of indocyanine green will be injected near the areola, and after a brief waiting period, the lymph nodes will be identified and removed. The study will compare the effectiveness of lymph node detection using both tracers to evaluate any improvements in detection rates.

Who should consider this trial

Good fit: Ideal candidates are patients over 18 years of age with breast cancer who are eligible for sentinel lymph node detection.

Not a fit: Patients who have undergone lymphadenectomy will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate lymph node detection, potentially improving surgical outcomes for breast cancer patients.

How similar studies have performed: While the use of indocyanine green in lymph node detection is gaining attention, this specific approach is relatively novel and has not been extensively tested in this context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients \>18 years of age with breast cancer who are candidates for sentinel lymph node detection will be included.
* N0 patients or patients who have undergone target axillary detection with good response

Exclusion Criteria:

* Lymphadenectomy

Where this trial is running

Cerdanyola del Vallès, Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancerlymph node detectionindocyanine greenbreast cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.