Using hyperbaric oxygen therapy to treat pain in sickle cell anemia
Hyperbaric Oxygen Therapy in Sickle Cell Pain
This study is testing if hyperbaric oxygen therapy can help adults with sickle cell anemia feel less pain during a pain crisis and recover faster.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | University of Nebraska Academic / other |
| Locations | 1 site (Omaha, Nebraska) |
| Trial ID | NCT03412045 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of hyperbaric oxygen (HBO) therapy on patients experiencing an uncomplicated acute pain crisis due to sickle cell anemia. Participants aged 19 and older will receive 1-3 sessions of HBO therapy, each lasting approximately two hours, to assess its impact on pain levels and hospital length of stay. Pain will be evaluated using a visual analog scale before and after treatment. The goal is to determine if HBO therapy can effectively reduce pain and improve recovery times for these patients.
Who should consider this trial
Good fit: Ideal candidates are adults aged 19 and older who present with an uncomplicated sickle cell crisis.
Not a fit: Patients with complicated sickle cell crises or those under 19 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce pain and shorten hospital stays for patients suffering from sickle cell crises.
How similar studies have performed: While some previous studies have suggested benefits of HBO therapy for sickle cell pain, results have been inconsistent and this approach remains largely untested in larger populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 19 years old or older * Present with an uncomplicated sickle cell crisis at admission friom the emergency department Exclusion Criteria: * \< 19 years old * pregnant female * complicated sickle cell crisis present (i.e., concomitant MI, stroke, acute chest syndrome at time of presentation)
Where this trial is running
Omaha, Nebraska
- Unversity of Nebraska Medical Center — Omaha, Nebraska, United States (Recruiting)
Study contacts
- Principal investigator: Jeff S Cooper, MD — University of Nebraska
- Study coordinator: Jeff S Cooper, MD
- Email: jeffrey.cooper@unmc.edu
- Phone: 402-552-2490
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.