Using hyperbaric oxygen therapy to improve insulin resistance in postmenopausal women
Effect of Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopausal Women
This study is testing if hyperbaric oxygen therapy can help improve insulin resistance in postmenopausal women who are struggling with high blood sugar levels.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 55 Years to 65 Years |
| Sex | Female |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Trial ID | NCT06806345 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of hyperbaric oxygen therapy on insulin resistance in postmenopausal women aged 55-65 with a BMI of 30-34.9 kg/m². Participants will receive hyperbaric oxygen therapy alongside hypoglycemic drugs to assess improvements in blood glucose levels and overall function. The study aims to identify clinical predictors that could enhance treatment efficiency and prevent complications associated with insulin resistance. By focusing on this demographic, the research seeks to address a significant public health issue in Egypt related to diabetes and cardiovascular diseases.
Who should consider this trial
Good fit: Ideal candidates are postmenopausal women aged 55-65 with insulin resistance and a BMI between 30-34.9 kg/m² who are already managing their blood glucose levels with oral hypoglycemic drugs.
Not a fit: Patients with chronic obstructive pulmonary disease, cardiac pacemakers, epilepsy, physical disabilities, or other ulcer-causing disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this therapy could provide a novel treatment option for managing insulin resistance and improving the quality of life for postmenopausal women.
How similar studies have performed: While hyperbaric oxygen therapy has shown promise in various conditions, this specific application for insulin resistance in postmenopausal women is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * A)Inclusion Criteria * All females were clinically diagnosed with Postmenopausal Insulin resistance. * Their ages were ranged from 55-65 years old. * Their BMI was 30-34.9 kg/m². * All patients should had controlled blood glucose levels by oral hypoglycemic drugs. * All patients should had cardiac Ejection Fraction \>or =50%. * Their Chest X-ray reported normal. * Their Ear ,nose , thorax will be clinically evaluated by a specialized ENT physician to ensure fitting for hyperbaric chamber * Voluntary acceptance of participation in the study . B)Exclusion Criteria: Participants will be excluded if they have : * Chronic obstructive pulmonary disease. * Cardiac pacemakers. * Epileptic fits. * Physically disable . * Any disorder that lead to ulcers other than diabetes such as ahistory of chronic peripheral arterial disease. Exclusion Criteria: \-
Where this trial is running
Cairo, Cairo Governorate
- Kobry el koba military complex — Cairo, Cairo Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: Siham mohamed fahmy Head of Hyperbaric oxygen therapy unit, Assistant professor
- Email: Fahmysiham@gmail.com
- Phone: 01033380185
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.