Using Hydroxyephedrine PET/CT to Diagnose Sympathetic Nervous System Diseases
Official title: Hydroxyephedrine PET/CT in Sympathetic Nervous System Diseases
Run by Tianjin Medical University · NCT06951984 · Data updated 2026-11-12
This study is testing a new type of imaging scan to see if it can help doctors better diagnose nerve-related diseases in adults with suspected or confirmed cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Tianjin Medical University Academic / other |
| Locations | 1 site (Tianjin, Tianjin Municipality) |
| Status | Recruiting |
| Started | March 1, 2013 |
| Main results expected | March 1, 2028 |
| Study ends | March 1, 2028 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT06951984 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adult patients aged 18 and older with suspected or newly diagnosed malignant tumors.
✕Probably not a fit
Patients with non-malignant lesions or those who are pregnant will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of 11C/18F-HED positron emission tomography/computed tomography (PET/CT) in diagnosing primary and metastatic lesions in patients with various sympathetic nerve-related diseases. Participants, who are adults with suspected or diagnosed malignant tumors, undergo PET/CT scans to assess lesion uptake and quantify results using the maximum standard uptake value (SUVmax). The study aims to calculate the sensitivity, specificity, and accuracy of this imaging technique for better diagnosis and management of these conditions.
Why it matters
Potential benefit: If successful, this study could enhance diagnostic accuracy for patients with sympathetic nervous system diseases, leading to improved treatment outcomes.
How similar studies have gone: Other studies have shown promising results using PET/CT imaging for similar diagnostic purposes, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated malignant tumors (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled HED PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee. Exclusion Criteria: * (i) patients with non-malignant lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.
Where it's running
-
Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Haonan Yu, MD
- Email: dreamadam@126.com
- Phone: +8613821000597
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Understanding Sympathetic Nerve Activity in COPD Patients
This study is trying to understand how the nervous system is overactive in people with COPD and what factors might be causing it.
-
GPIIb/IIIa PET/CT Imaging for Thrombi in the Brain and Body
This study tests an imaging tracer called 18F/68Ga-GP1 to see if it safely helps identify thrombi in adults who might have them.
-
MAO-B PET/CT imaging in Parkinson’s-related diseases
This study tests whether 18F-FPyCO/SMBT-1 PET/CT can help diagnose Parkinson’s-related conditions by measuring lesion uptake in patients with PD, PD dementia, or parkinsonism.
-
18F-AIPF-1026 PET/CT for MAO-A related diseases in adults
A PET/CT test using 18F-AIPF-1026 is being looked at to see if it can help diagnose primary and metastatic lesions in adults with MAO-A–related conditions like depression, anxiety, and heart injuries.
-
PD-L1 PET/CT to see primary and metastatic PD-L1-related lesions in adults
This study tests whether 68Ga/18F-PD-L1 PET/CT can help detect primary and metastatic PD-L1-related tumors in adults.
-
SNRK and vascular aging in adults
This study tests whether SNRK related signals in vascular cells relate to aging of the arteries in adults.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.