Clinical trial Recruiting at 1 site Observational Ages 18 to 80

Using Hydroxyephedrine PET/CT to Diagnose Sympathetic Nervous System Diseases

Official title: Hydroxyephedrine PET/CT in Sympathetic Nervous System Diseases

Run by Tianjin Medical University · NCT06951984 · Data updated 2026-11-12

This study is testing a new type of imaging scan to see if it can help doctors better diagnose nerve-related diseases in adults with suspected or confirmed cancer.

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment500 (estimated)
SponsorTianjin Medical University
Academic / other
Locations1 site (Tianjin, Tianjin Municipality)
StatusRecruiting
StartedMarch 1, 2013
Main results expectedMarch 1, 2028
Study endsMarch 1, 2028
Registry record updatedSeptember 8, 2026
Trial IDNCT06951984 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adult patients aged 18 and older with suspected or newly diagnosed malignant tumors.

Probably not a fit

Patients with non-malignant lesions or those who are pregnant will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of 11C/18F-HED positron emission tomography/computed tomography (PET/CT) in diagnosing primary and metastatic lesions in patients with various sympathetic nerve-related diseases. Participants, who are adults with suspected or diagnosed malignant tumors, undergo PET/CT scans to assess lesion uptake and quantify results using the maximum standard uptake value (SUVmax). The study aims to calculate the sensitivity, specificity, and accuracy of this imaging technique for better diagnosis and management of these conditions.

Why it matters

Potential benefit: If successful, this study could enhance diagnostic accuracy for patients with sympathetic nervous system diseases, leading to improved treatment outcomes.

How similar studies have gone: Other studies have shown promising results using PET/CT imaging for similar diagnostic purposes, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated malignant tumors (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled HED PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria:

* (i) patients with non-malignant lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Where it's running

  • Tianjin Medical University General Hospital
    Tianjin, Tianjin Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.