Using hydrocortisone to improve treatment outcomes for infantile intussusception
Effect of Hydrocortisone on Improving Outcome of Pneumatic Reduction of Infantile Intussusception: A Randomized Controlled Trial
This study tests if giving hydrocortisone to infants with intussusception before a treatment can help make that treatment work better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 3 Months to 4 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT02691858 on ClinicalTrials.gov |
What this trial studies
This study investigates the effect of hydrocortisone on the success rate of pneumatic reduction in infants with intussusception. Infants in the experimental group will receive a single dose of IV hydrocortisone prior to the first attempt at pneumatic reduction, while the control group will receive saline. The outcomes of both groups will be measured to determine if hydrocortisone improves the effectiveness of the treatment. The study aims to reduce the number of attempts needed for successful reduction and enhance overall patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are infants diagnosed with intussusception.
Not a fit: Patients with peritonitis, pneumoperitoneum, or those who are morbid may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to higher success rates in treating infantile intussusception with fewer attempts required for reduction.
How similar studies have performed: While the use of hydrocortisone in this context is novel, similar studies have shown promising results in other pediatric conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Infantile Intussusception Exclusion Criteria: * Peritonitis Pneumoperitoneum Morbid patients
Where this trial is running
Cairo
- Cairo University Pediatric Hospital — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Mostafa Gad, MSc
- Email: mostafagad@kasralainy.edu.eg
- Phone: 201002265009
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.