Clinical trial Recruiting at 1 site Interventional Ages 18 to 45 Women only

Using hyaluronic acid gel to prevent adhesions after surgery for retained pregnancy tissue

Official title: The Efficacy of Auto-crosslinked Hyaluronic Acid Gel in the Prevention of Adhesion Reformation After Hysteroscopic Resection of Retained Products of Conception:a Randomized Controlled Trial

Run by Fu Xing Hospital, Capital Medical University · NCT05085067 · Data updated 2026-11-12

This study is testing if a special gel can help prevent complications like infertility after surgery for leftover pregnancy tissue.

More Retained Products of Conception trials

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexWomen only
Enrollment86 (estimated)
SponsorFu Xing Hospital, Capital Medical University
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedApril 1, 2022
Main results expectedApril 30, 2025
Study endsMay 30, 2025
Registry record updatedMarch 12, 2025
Trial IDNCT05085067 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women diagnosed with retained products of conception who are undergoing hysteroscopic resection.

Probably not a fit

Patients with severe complications from surgery or those with active genital tract infections may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of auto-cross linked hyaluronic acid gel in preventing the reformation of intrauterine adhesions following hysteroscopic resection of retained products of conception (RPOC). RPOC can lead to complications such as infertility and menstrual abnormalities if not treated properly. The study will randomly assign patients who have undergone the surgical procedure to receive either the gel or standard care, allowing for a comparison of outcomes related to adhesion formation. The goal is to determine if the gel can reduce the risk of complications associated with RPOC treatment.

Why it matters

Potential benefit: If successful, this treatment could significantly improve fertility outcomes for patients who have experienced retained products of conception.

How similar studies have gone: While the use of hyaluronic acid gel in this context is promising, similar studies have shown mixed results, indicating that this approach may still be novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of retained products of conception
* Written consent obtained

Exclusion Criteria:

* Patients with severe complications of medicine and surgery
* Acute or chronic genital tract inflammation
* No understanding or approving the randomized controlled trial

Where it's running

  • FuxingHospital,Captital Medical University
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.