Using honey phonophoresis to improve knee cartilage thickness in osteoarthritis patients
Influence of Honey Phonophoresis on Cartilage Thickness in Patients With Knee Osteoarthritis
This study is testing if using honey in a special treatment can help improve knee cartilage thickness and reduce symptoms for people with osteoarthritis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years to 65 Years |
| Sex | All |
| Sponsor | University of Jazan Government |
| Locations | 2 sites (Jazan, Gizan and 1 other locations) |
| Trial ID | NCT06202092 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of honey phonophoresis on knee cartilage thickness in patients with bilateral mild-to-moderate medial tibiofemoral osteoarthritis. The study involves a double-blinded, randomized control design where participants will be divided into two treatment groups. One group will receive phonophoresis treatment using honey, while the other will receive conventional physiotherapy. The trial aims to assess the potential regenerative properties of honey on articular cartilage and its ability to alleviate symptoms associated with osteoarthritis.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40 to 65 with bilateral mild-to-moderate medial tibiofemoral osteoarthritis.
Not a fit: Patients with severe knee osteoarthritis or other rheumatologic conditions will not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could enhance cartilage regeneration and improve knee function in patients with osteoarthritis.
How similar studies have performed: While the use of honey in medical treatments is gaining interest, this specific approach of phonophoresis for knee cartilage regeneration is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * bilateral mild-to-moderate medial tibiofemoral Osteoarthritis Exclusion Criteria: 1. rheumatologic conditions such as: * rheumatoid arthritis, * severe knee OA, * thrombosis of the lower limbs, 2. patients who had physiotherapy treatment of the knee in the previous 6 months, 3. a history of injections in the knee joint during the last 6 months, * balance disorders, * neuropathy or sensory disorders, * skin damage around the knee, * previous surgery on the knee joint, or a previous fracture of the lower extremity with knee joint involvement. 4. Patients will be also excluded if they have any contraindications or precautions for the use of ultrasound (e.g., infection, heart problems, pacemaker, metal implants, open epiphysis, pregnancy, thrombophlebitis, or impaired sensation)
Where this trial is running
Jazan, Gizan and 1 other locations
- Jazan University — Jazan, Gizan, Saudi Arabia (Recruiting)
- Jazan University — Jazan, Gizan, Saudi Arabia (Recruiting)
Study contacts
- Principal investigator: Abdelrahman Elsayegh, Associate professor — University of Jazan
- Study coordinator: Mohamed M Ahmed, Assistant Professor
- Email: mmahmed@jazanu.edu.sa
- Phone: +966562819650
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.