Using high-resolution MRI to improve diagnosis of optic disc edema
Precise High Resolution MRI to Increase Accuracy and Gain Confidence to Diagnose Patients With Optic Disc Edema
This study is testing if using advanced MRI scans can help doctors better diagnose the causes of optic disc swelling in patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris) |
| Trial ID | NCT04448613 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the diagnostic accuracy for patients presenting with optic disc edema by utilizing advanced high-resolution MRI techniques. The study focuses on identifying the underlying causes of optic disc swelling, which can be indicative of various ophthalmologic and neurological conditions. By employing MRI as a first-line diagnostic tool, the study seeks to provide rapid and precise etiological diagnoses, particularly in cases of inflammatory or compressive pathologies. Participants will undergo MRI scans to assess the effectiveness of these new imaging sequences in diagnosing conditions such as intracranial hypertension and ischemic optic neuropathy.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who exhibit clinically detected papillary edema at the back of the eye.
Not a fit: Patients who have contraindications for MRI, such as those with electrical devices or claustrophobia, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses for patients with optic disc edema, improving treatment outcomes.
How similar studies have performed: Other studies utilizing advanced MRI techniques for diagnosing optic nerve conditions have shown promising results, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years old * presenting a papillary edema detected clinically at the back of the eye * Express consent to participate in the study * Affiliate or beneficiary of a Social Security scheme Exclusion Criteria: * MRI contraindication (electrical device, metallic foreign body, claustrophobia) * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman
Where this trial is running
Paris
- Fondation Ophtalmologique Adolphe de Rothschild (FOR) — Paris, France (Recruiting)
Study contacts
- Study coordinator: amé YAVCHITZ
- Email: ayavchitz@for.paris
- Phone: 0148036431
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.