Using high-flow nasal oxygen to prevent lung collapse during anesthesia in obese patients
The Effect of High-flow Nasal Cannula Applied During Preoxygenation for Prevention of Atelectasis in Patients With Obesity Undergoing General Anesthesia: A Randomized Controlled Trial
This study is testing if using high-flow nasal oxygen can help prevent lung collapse during anesthesia in obese adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 92 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06205212 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of high-flow nasal oxygenation during preoxygenation to reduce the incidence of pulmonary atelectasis in obese patients undergoing general anesthesia. The focus is on adult patients with a BMI of 30 kg/m2 or greater, as they are at higher risk for atelectasis. Participants will receive high-flow nasal oxygen or facemask oxygen during the induction of anesthesia. The study aims to determine if this intervention can improve respiratory outcomes in this specific patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients with a BMI of 30 kg/m2 or greater scheduled for surgery under general anesthesia.
Not a fit: Patients with severe cardiac or respiratory diseases, or those with a history of difficult airway management, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the risk of lung collapse during surgery for obese patients, leading to better postoperative recovery.
How similar studies have performed: While the specific approach of using high-flow nasal oxygen in this context may be novel, similar studies have shown promising results in improving respiratory outcomes during anesthesia.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults patients undergoinig surgery under general anesthesia with a BMI of 30 kg/m2 or greater who have given informed consent Exclusion Criteria: * surgery time less than 2 hours * Nasotracheal intubation * Severe cardiac or respiratory disease * History of difficult airway * History of a surgery or anatomical anomaly in the head and neck * History of Inability to breathe through nose * Gastric reflux disease
Where this trial is running
Seoul
- SMG - SNU Boramae Medical Center — Seoul, Korea, Republic of (Recruiting)
Study contacts
- Principal investigator: Tae Kyong Kim — SMG-SNU Boramae Medical Center
- Study coordinator: Tae Kyong Kim
- Email: ktkktk@gmail.com
- Phone: 82-2-870-2519
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.