Using high-flow nasal oxygen to help trauma patients after extubation
High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients
This study is testing if high-flow nasal oxygen can help trauma patients breathe better after being taken off a ventilator and reduce the chances of needing to be put back on one.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 450 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hamad Medical Corporation Industry-sponsored |
| Locations | 1 site (Doha) |
| Trial ID | NCT06110390 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of high-flow nasal oxygen therapy in preventing extubation failure among adult trauma patients in the intensive care unit. It aims to address the high rates of re-intubation, which can lead to increased morbidity and longer hospital stays. The study will focus on patients who are intubated and ventilated due to trauma and are deemed fit for extubation. By utilizing high-flow nasal oxygen, the researchers hope to improve patient outcomes and reduce the complications associated with extubation failure.
Who should consider this trial
Good fit: Ideal candidates for this study are adult trauma patients who are intubated and ventilated and are considered fit for extubation.
Not a fit: Patients who cannot be extubated, such as those requiring tracheostomy or with specific facial injuries, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the need for re-intubation and improve recovery times for trauma patients.
How similar studies have performed: While high-flow nasal oxygen has been studied in other critical care settings, this specific application in trauma intensive care patients is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult intubated and ventilated patients who are victims of trauma and are being cared for on the Trauma Intensive Care Unit will be considered eligible for the study when they are considered fit for extubation. Exclusion Criteria: * Patients who cannot be extubated (including patients requiring tracheostomy) * Patients with cribriform plate fractures * Patients with nasal occlusion for any reason * Patients with unstable mid-face fractures
Where this trial is running
Doha
- Hamad General Hospital — Doha, Qatar (Recruiting)
Study contacts
- Study coordinator: Gustav F Strandvik, MBChB
- Email: gstrandvik@hamad.qa
- Phone: +97440253769
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.