Clinical trial Recruiting at 1 site Interventional Ages Any age to 5

Using HEPA air purifiers to improve indoor air quality in rural Alaska homes

Official title: The Clean Air Study: High Efficiency Particulate Air (HEPA) Purifiers to Improve Indoor Air Quality and Health in Rural Alaska Homes

Run by Alaska Native Tribal Health Consortium · NCT06534385 · Data updated 2026-11-12

This study is testing if using HEPA air purifiers in homes can help improve the breathing health of Alaska Native children living in rural areas with poor air quality.

Quick facts

Study typeInterventional
AgesAny age to 5 Years
SexAll
Enrollment15 (estimated)
SponsorAlaska Native Tribal Health Consortium
Academic / other
Locations1 site (Bethel, Alaska)
StatusRecruiting
StartedNovember 25, 2024
Main results expectedApril 1, 2026
Study endsApril 1, 2026
Registry record updatedFebruary 27, 2025
Trial IDNCT06534385 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Alaska Native families residing in homes that use woodstoves for heating or have tobacco smokers present.

Probably not a fit

Patients who plan to move during the study period or already use HEPA air purifiers will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on improving indoor air quality in homes of Alaska Native children in the Yukon-Kuskokwim Delta, where poor air quality is linked to respiratory diseases. Participants will use HEPA air purifiers to reduce particulate matter (PM2.5) in their homes, which is often elevated due to wood stove use and tobacco smoke. Families will monitor their child's respiratory symptoms weekly over a 12-week period while using the air purifiers. The goal is to assess the impact of improved air quality on the health of these children.

Why it matters

Potential benefit: If successful, this study could lead to significant improvements in respiratory health for children living in homes with poor air quality.

How similar studies have gone: Previous studies have shown that HEPA air purifiers can effectively reduce indoor air pollution, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Alaska Native participants residing in homes where woodstoves are used for heat or a smoker resides in the home.

Exclusion Criteria:

* Plan to move homes during the study period.
* Using HEPA air purifiers (other than the ones provided by the study).

Where it's running

  • Yukon Kuskowkim Health Corporation
    Bethel, Alaska, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.