Using heat therapy to treat warts in special populations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of local hyperthermia, specifically using an infrared thermotherapy apparatus, to treat viral warts in various special populations, including pregnant women, children, and patients with autoimmune diseases or HIV. The approach aims to mobilize the body's immune response to eliminate HPV infections, with previous research indicating a cure rate of 45-55%. The study is designed to assess the safety and efficacy of this method compared to traditional treatments, which often have higher recurrence rates and more trauma.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Pregnant women with viral warts
2. Diagnosis of AIDS with viral warts
3. Autoimmune disease patients with viral warts
4. Diabetic patients with viral warts
5. Patients with viral warts who are currently being treated with immunosuppressants
6. Children with viral warts
7. The subject or legal guardian is able to understand and sign the informed consent/consent to participate in the study

Exclusion Criteria:

1. The subject suffers from tumor or other serious disease and cannot complete this clinical study
2. Timely treatment and follow-up cannot be guaranteed due to personal or other objective reasons

Where it's running

• The First Affiliated Hospital of China Medical University
  Shenyang, Liaoning, China Recruiting

Study contacts

• Study coordinator: Wei Huo, Doctor
• Email: huozhongfang@163.com
• Phone: 024-83282524

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Cantharidin and occlusion in verruca epithelium: testing a topical treatment for common warts

  This Phase 3 study tests VP-102/TO-208 (cantharidin) vs. a vehicle to see if it clears common warts in people 2 years and older who have a normal immune system.

  Recruiting at 14 sites Phase 3 Verrica Pharmaceuticals Inc. · San Diego, California and 19 other locations · NCT07637734

• Heat combined with a hydrogen peroxide microneedle patch for common warts.

  This test will see if applying local heat at 44°C together with a microneedle patch that delivers 3% hydrogen peroxide clears common hand and foot warts in people aged 6 to 65.

  Recruiting First Hospital of China Medical University · Shenyang · NCT07534865

• Long-term follow-up of cantharidin (YCANTH/VP-102/TO-208) treatment for common warts

  This follow-up will try applying cantharidin (YCANTH/VP-102/TO-208) every ~21 days for up to four applications to see if it safely clears remaining common warts in people who completed earlier COVE studies.

  Recruiting at 12 sites Phase 3 Verrica Pharmaceuticals Inc. · Saint Augustine, Florida and 11 other locations · NCT07457918

• Treatment of warts using heat and hydrogen peroxide

  This study is testing if using heat along with hydrogen peroxide can help people get rid of warts caused by a virus better than using either treatment alone.

  Recruiting at 2 sites First Hospital of China Medical University · Shenyang, Liaoning and 1 other locations · NCT06812065

• HPV vaccination for treating stubborn skin warts

  This study is testing if the HPV vaccine can help adults with stubborn skin warts get better compared to a placebo.

  Recruiting at 2 sites Phase 2/3 Western Institute for Veterans Research · Salt Lake City, Utah and 1 other locations · NCT05625633

• Using Candida antigen and a bivalent HPV vaccine to clear multiple common warts

  This study will test whether injections of Candida antigen, a bivalent HPV vaccine, or both can clear multiple common warts in people with persistent or widespread warts.

  Recruiting Phase 2 Zagazig University · Zagazig, Al Sharqia · NCT05291845

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.