Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using HD-tDCS to Study Brain Connectivity

Official title: Modulating Functional Brain Connectivity Using High Definition Transcranial Direct Current Stimulation (HD-tDCS)

Run by University of Manitoba · NCT05959551 · Data updated 2026-11-12

This study is testing how a brain stimulation technique called HD-tDCS affects brain connections in healthy people to see if it can be used better in treating conditions in the future.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorUniversity of Manitoba
Academic / other
Locations1 site (Winnipeg, Manitoba)
StatusRecruiting
StartedJuly 1, 2023
Main results expectedAugust 31, 2026
Study endsAugust 31, 2026
Registry record updatedMay 1, 2026
Trial IDNCT05959551 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy individuals without any history of neurological or psychiatric disorders.

Probably not a fit

Patients with neurological or psychiatric diseases, abnormal MRI results, or those with metal implants or cardiac pacemakers will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance our understanding of the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) by recruiting healthy individuals for a series of neuropsychological assessments and MRI scans. Participants will receive HD-tDCS while undergoing MRI, with four different stimulation targets being tested against a sham group. After the stimulation, participants will be re-evaluated using standardized neuropsychological tests to assess any changes in brain connectivity and function. The goal is to improve the clinical applications of HD-tDCS based on the findings.

Why it matters

Potential benefit: If successful, this study could lead to improved therapeutic applications of HD-tDCS for various neurological and psychiatric conditions.

How similar studies have gone: While the use of HD-tDCS is gaining traction, this specific approach to studying its effects on brain connectivity is relatively novel and has not been extensively tested in similar studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- All other than excluded.

Exclusion Criteria:

* History or susceptibility to any neurological or psychiatric diseases, particularly seizures
* abnormal MRI
* metal implants or a cardiac pacemaker
* pregnant or breastfeeding women

Where it's running

  • University of Manitoba
    Winnipeg, Manitoba, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.