Using HD-tDCS to Study Brain Connectivity
Modulating Functional Brain Connectivity Using High Definition Transcranial Direct Current Stimulation (HD-tDCS)
This study is testing how a brain stimulation technique called HD-tDCS affects brain connections in healthy people to see if it can be used better in treating conditions in the future.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Manitoba Academic / other |
| Locations | 1 site (Winnipeg, Manitoba) |
| Trial ID | NCT05959551 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance our understanding of the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) by recruiting healthy individuals for a series of neuropsychological assessments and MRI scans. Participants will receive HD-tDCS while undergoing MRI, with four different stimulation targets being tested against a sham group. After the stimulation, participants will be re-evaluated using standardized neuropsychological tests to assess any changes in brain connectivity and function. The goal is to improve the clinical applications of HD-tDCS based on the findings.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals without any history of neurological or psychiatric disorders.
Not a fit: Patients with neurological or psychiatric diseases, abnormal MRI results, or those with metal implants or cardiac pacemakers will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved therapeutic applications of HD-tDCS for various neurological and psychiatric conditions.
How similar studies have performed: While the use of HD-tDCS is gaining traction, this specific approach to studying its effects on brain connectivity is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- All other than excluded. Exclusion Criteria: * History or susceptibility to any neurological or psychiatric diseases, particularly seizures * abnormal MRI * metal implants or a cardiac pacemaker * pregnant or breastfeeding women
Where this trial is running
Winnipeg, Manitoba
- University of Manitoba — Winnipeg, Manitoba, Canada (Recruiting)
Study contacts
- Study coordinator: Ji Hyun Ko, PhD
- Email: ji.ko@umanitoba.ca
- Phone: 2042930724
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.