Using Harmonic Scalpel to Reduce Drainage After Lung Surgery

Use of Harmonic Scalpel to Decrease Lymphatic and Chest Tube Drainage After Lymph Node Dissection With Lobectomy. A Single Center Prospective Randomized Controlled Study.

Not applicable Interventional Sentara Cardiovascular Research Institute · NCT00591552

This study is testing if using a special tool called the Harmonic Scalpel during lung cancer surgery can help reduce drainage and the need for chest tubes, making recovery easier for patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages20 Years to 75 Years
SexAll
SponsorSentara Cardiovascular Research Institute Academic / other
Locations1 site (Norfolk, Virginia)
Trial IDNCT00591552 on ClinicalTrials.gov

What this trial studies

This study investigates whether the Harmonic Scalpel can effectively reduce lymphatic drainage and the need for chest tubes after lymph node dissection in lung cancer surgeries. Patients undergoing resection for stage 1, 2, or 3A lung cancer will be randomly assigned to receive either the Harmonic Scalpel or traditional electrocautery during their procedure. The primary goal is to determine if the Harmonic Scalpel leads to less drainage and shorter hospital stays compared to the control method. The study aims to provide evidence for the potential benefits of using this newer technology in surgical oncology.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20-75 with stage 1, 2, or 3A lung cancer who are scheduled for surgical resection.

Not a fit: Patients with a history of congestive heart failure, renal failure, bulky lymph nodes, or those who are pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to shorter hospital stays and improved recovery for lung cancer patients undergoing surgery.

How similar studies have performed: While there is no published data specifically supporting the use of the Harmonic Scalpel in this context, similar studies have shown promising results with advanced surgical techniques.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing resection for stage 1, 2 or 3A lung cancer.
* Patients between the ages of 20-75.

Exclusion Criteria:

* History of Congestive Heart Failure.
* History of renal failure, ie., creatinine greater than 2.2.
* Patients with bulky or matted lymph nodes in stage 3A.
* Current pregnancy.
* Current participation in another study involving an investigational device or drug.

Where this trial is running

Norfolk, Virginia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung CancerLung cancerLymph node dissection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.