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Using hair follicle secretome to improve recovery after aesthetic procedures

A Multi-site, Prospective, Observational Study of Autologous Hair Follicle Secretome (aHFS) as an Adjunct to Medical Aesthetic Procedures

Observational Acorn Biolabs Inc. · NCT06477172

This study looks at whether a special product made from hair follicles can help people recover better after cosmetic procedures.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorAcorn Biolabs Inc. Industry-sponsored
Locations40 sites (Birmingham, Alabama and 39 other locations)
Trial IDNCT06477172 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather real-world data on the application of an autologous hair follicle derived secretome topical product following various medical aesthetic procedures. Participants will include individuals planning to undergo such procedures and who intend to use the secretome product. The study will track outcomes related to post procedural erythema and overall recovery. It is designed to be non-interventional, meaning that it will observe the effects of the product without altering the standard care provided to participants.

Who should consider this trial

Good fit: Ideal candidates are males and females aged 18-60 who are planning a medical aesthetic procedure and intend to use the hair follicle secretome product.

Not a fit: Patients who are pregnant, breastfeeding, or have recently participated in another clinical trial may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance recovery and reduce redness after aesthetic procedures for patients.

How similar studies have performed: While this approach is relatively novel, similar studies exploring the use of autologous products in aesthetic procedures have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Male and Female
* Ages: 18-60
* Any Fitzpatrick skin type
* Planning a medical aesthetic procedure
* For subjects receiving hair procedures (closed to enrollment):

  1. Androgenic alopecia
  2. Traction alopecia
  3. Scarring alopecia
  4. Stable use of any medication or supplement for hair loss, including finasteride, any other 5 α-reductase inhibitor, minoxidil, steroids, or hormonal products, during the 3 months prior to enrollment in the study is allowed.
  5. No intention to start new hair growth medications or change dose of hair growth medications from the time of consent through the end of the study follow-up period.
* Undergoing one of the following medical aesthetic procedures:

  1. Laser resurfacing of the face (ablative or non-ablative) or Ellacor of the face (Ellacor closed to enrollment)
  2. Tixel of the face
  3. Keralase of the scalp (scalp treatment closed to enrollment)
  4. Acne Scars and Surgery scars, either old or new as long as old scars are also being treated with ablative or non-ablative laser or microneedling (e.g. abdominoplasty, breast reduction/ reconstruction/enhancement, post-weight loss, etc.
* Planning to use Acorn Autologous Hair Follicle Secretome cosmetic product

Exclusion Criteria:

* Pregnant or Breastfeeding
* Participation in an interventional clinical trial in the last 30 days
* Use of other topical cosmetic products that may confound results
* Use of retinoids within 7 days prior to facial procedure
* For those receiving hair treatment, must not have had a hair transplant in the treatment area within the past 12 months
* Any health condition that in the investigator's opinion should preclude participation in study

Where this trial is running

Birmingham, Alabama and 39 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Post Procedural Erythema
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.