Using green light and brain stimulation to treat migraines

Green Light and Transcranial Direct Current Stimulation in Migraine Patients; a Randomized Control Trial.

NA · Riphah International University · NCT06212869

This study is testing whether green light therapy and a brain stimulation technique can help people with migraines feel better and have fewer headaches.

Quick facts

PhaseNA
Study typeInterventional
Enrollment45 (estimated)
Ages18 Years and up
SexAll
SponsorRiphah International University (other)
Locations1 site (Rawalpindi, Punjab)
Trial IDNCT06212869 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of green light exposure and transcranial direct current stimulation (tDCS) on patients suffering from migraines. It aims to address the lack of evidence regarding the clinical outcomes of these novel treatments by conducting a larger-scale trial. Participants will receive either active tDCS, sham tDCS, or green light therapy to evaluate the effectiveness of these interventions in reducing migraine frequency and severity. The study will include patients who meet specific diagnostic criteria for migraines as defined by the International Headache Society.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with migraines who experience frequent headache attacks and meet specific inclusion criteria.

Not a fit: Patients with mental illness, photophobia, cranial implants, brain tumors, or skull wounds may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide new, non-pharmacological treatment options for patients suffering from migraines.

How similar studies have performed: While there have been smaller studies on similar interventions, this approach of comparing tDCS with green light therapy for migraines is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Meet the diagnostic criteria established by the International Headache Society,
* patient must have had at least 5 headache attacks that lasted 4-72 hours (untreated or unsuccessfully treated)
* headache must have had at least 2 of the following characteristic; Unilateral location \& Pulsating quality,
* An average headache pain intensity of migraine episodes of ≥5 at numeric pain scale (NPS) over the 10 weeks prior to enrolling in the study.

Exclusion Criteria:

* Mental illness,
* Photophobic individual,
* Presence of shunt and/or implant at the cranial region,
* Brain tumors,
* Wound at skull

Where this trial is running

Rawalpindi, Punjab

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Migraine, migraine, green light, transcranial direct current stimulation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.