Using glass-ionomer sealing to treat hypersensitive teeth in children

Evaluation of Efficiency, Acceptance and the Durability of Glass-Ionomer Sealing Technique on Hypersensitive MIH (Molar Incisor Hypomineralisation) Teeth With and Without Enamel Breakdown - a Cohort Study

Not applicable Interventional University Medicine Greifswald · NCT05945381

This study is testing if a special sealant can help reduce tooth sensitivity in children and teens with certain dental issues.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment18 (estimated)
Ages6 Years to 17 Years
SexAll
SponsorUniversity Medicine Greifswald Academic / other
Locations1 site (Greifswald)
Trial IDNCT05945381 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a glass-ionomer sealing technique on hypersensitive molars affected by molar incisor hypomineralization (MIH) in children and adolescents. It involves a single-arm cohort design where the degree of tooth sensitivity is assessed before and after the application of the sealant, both immediately and after three months. The study aims to determine the acceptance, durability, and efficiency of this treatment method, utilizing the Schiff Cold Air Sensitivity Test and Wong-Baker Faces Rating Scale for evaluation. Conducted at the University of Greifswald, the study will run from May 2023 to Autumn 2024.

Who should consider this trial

Good fit: Ideal candidates are children and adolescents with self-reported hypersensitive MIH molars who do not have systemic health issues.

Not a fit: Patients with acute dental pain, systemic diseases requiring special attention, or allergies to the sealing material may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly reduce tooth sensitivity in children with MIH, improving their quality of life.

How similar studies have performed: While similar approaches have been explored, this specific application of glass-ionomer sealing for MIH hypersensitivity is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-reported hypersensitive MIH molar (MIH-TNI 3 \& 4a/b/c).
* Children \& adolescents without systematic health diseases.
* No sealing therapy or application of desensitizing agent on the MIH-teeth within 1 month before participation in the study.
* Agreement to voluntary participation in the study.

Exclusion Criteria:

* Patients with acute pain/ patients with signs or symptoms to be treated.
* Patients with systemic disease that require special attention during their dental treatment.
* Parents / children who refused to participate in the study. - MIH teeth with signs of irreversible pulpitis.
* Allergy against any ingredients of the material.

Where this trial is running

Greifswald

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HypersensitiveMolar Incisor HypomineralizationPit and Fissure Sealants
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.