Using genetic testing to personalize treatment for PTSD in veterans

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational clinical trial evaluates the effectiveness of pharmacogenetic testing (PGx) to tailor mental health treatments for veterans and members of the Canadian Armed Forces and Royal Canadian Mounted Police. Participants, including both psychiatrists and patients, will complete surveys to assess their knowledge and attitudes towards PGx. Patients can choose to opt-in for PGx-guided treatment, which involves sharing genetic test results with their psychiatrists to inform treatment planning. The study aims to gather insights on the integration of PGx in clinical practice and its impact on treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Provider participant:

  * Are at least 18 years of age;
  * Speak and write English;
  * Currently working as an OSI Clinic Psychiatrist at the London St. Joseph's OSI Clinic.

    * Psychiatrist with an active caseload of patients being treated for OSIs.
* Patient participant:

  * Veteran (patient) CAF or RCMP member;
  * Are at least 18 years of age;
  * Are a current patient at the London St. Joseph's OSI Clinic;
  * Current diagnosis of an OSI;
  * Speak and write English;
  * Consents to the use of CROMIS data for the purpose of this study; and
  * Consents to the use of prior OSI Clinic data for research purposes (if you have been a patient at the OSI Clinic prior to this study, the research team will use past OSI Clinic data to observe changes over time).

Exclusion Criteria:

* Participants (provider or patients) who are unable to, or do not, provide informed consent for participation.

Where it's running

• MacDonald Franklin OSI Research and Innovation Centre
  London, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Natalie Ein, PhD
• Email: natalie.ein@sjhc.london.on.ca
• Phone: 416-573-9047

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.