Using genetic testing to improve medication safety for children
Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System
This study is testing whether genetic testing can help doctors choose safer medications for children to reduce the risk of bad reactions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Sex | All |
| Sponsor | University of British Columbia Academic / other |
| Locations | 2 sites (Vancouver, British Columbia and 1 other locations) |
| Trial ID | NCT04249375 on ClinicalTrials.gov |
What this trial studies
This project focuses on reducing adverse drug reactions in children by implementing a pharmacogenomic testing program. It aims to evaluate the safety and effectiveness of commonly prescribed medications, including antibiotics, analgesics, and mental health drugs. The study will involve collecting patient information from physicians and developing reports to communicate test results to healthcare providers and families. Additionally, it will assess how these tests and results are understood and utilized by all stakeholders involved.
Who should consider this trial
Good fit: Ideal candidates include children whose physicians are considering or currently prescribing medications that are part of the pharmacogenomic testing panels.
Not a fit: Patients who do not speak or understand English may not benefit from this study due to communication barriers.
Why it matters
Potential benefit: If successful, this approach could significantly enhance medication safety and effectiveness for pediatric patients.
How similar studies have performed: Other studies have shown promise in using pharmacogenomic testing to improve medication outcomes, indicating that this approach is both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants will be enrolled if they can benefit from pharmacogenomic testing. This means their physician is considering the use of a drug that is part of the panels (analgesics, antibiotics, and mental health medication) or they are already using one. Exclusion Criteria: * Patients who do not speak or understand English.
Where this trial is running
Vancouver, British Columbia and 1 other locations
- Children's and Women's Health Centre of British Columbia — Vancouver, British Columbia, Canada (Recruiting)
- Children's Hospital of Eastern Ontario — Ottawa, Ontario, Canada (Recruiting)
Study contacts
- Study coordinator: Bruce Carleton, PharmD.
- Email: bcarleton@popi.ubc.ca
- Phone: 604-875-2179
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.