Using genetic testing to improve cancer prevention in older adults

Strategic Targeting for Optimal Prevention of Cancer

Observational ClinLogic LLC · NCT03897374

This study is testing if genetic testing can help older adults understand their risk for cancer and guide doctors in finding and treating it earlier.

Quick facts

Study typeObservational
Enrollment120000 (estimated)
Ages65 Years and up
SexAll
SponsorClinLogic LLC Industry-sponsored
Locations1 site (Prosper, Texas)
Trial IDNCT03897374 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect data from individuals aged 65 and older to evaluate the benefits of hereditary cancer genomic diagnostics in assessing genetic cancer risk. The study focuses on guiding physicians in implementing preventative measures that may lead to early detection and treatment of cancer. Participants must have a medical necessity for genetic testing, which will be ordered by their physician based on individual care considerations. The genes evaluated may change over time as new information becomes available, ensuring that the testing remains relevant and comprehensive.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 65 and older who have a history of cancer or a family member with cancer and meet medical necessity for genetic testing.

Not a fit: Patients who are currently hospitalized, incarcerated, or unable to provide accurate medical history due to mental incapacity will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance early cancer detection and improve treatment outcomes for older adults at risk.

How similar studies have performed: Other studies have shown promise in using genetic testing for cancer risk assessment, indicating that this approach is supported by prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Study subjects may be included in the Clinical Trial if they meet all of the following inclusion criteria:

  * individuals, ages 65 years or older;
  * must have met medical necessity for hereditary cancer genomic testing and allowed the physician to test based on medical necessity;
  * hereditary cancer diagnostic test was ordered by a physician related to individual subject care considerations.
  * study subject has or had cancer
  * study subject has at least one family member with cirrent or past cancer

Exclusion Criteria:

* Study subjects will be excluded from the study if any of the following criteria apply: • study subject is currently hospitalized or incarcerated;

  * study subject is unable to provide an accurate history due to mental incapacity
  * study subject is currently abusing illicit and/or prescription drugs;

Where this trial is running

Prosper, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Early Detection of Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.