Clinical trial Recruiting at 2 sites Observational Ages 18 to 90

Using gastric ultrasound to improve airway management in patients on GLP-1 medications

Official title: Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)

Run by Clinica Universidad de Navarra, Universidad de Navarra · NCT06666049 · Data updated 2026-11-12

This study is testing if using ultrasound to check stomach contents can help doctors manage the airways of patients on GLP-1 medications before surgery to lower the risk of aspiration pneumonia.

More Aspiration Pneumonia trials

Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexAll
Enrollment39 (estimated)
SponsorClinica Universidad de Navarra, Universidad de Navarra
Academic / other
Locations2 sites (Madrid, Madrid and 1 other locations)
StatusRecruiting
StartedOctober 21, 2024
Main results expectedNovember 1, 2026
Study endsDecember 1, 2026
Registry record updatedMay 5, 2026
Trial IDNCT06666049 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years taking GLP-1 analog medications and classified as ASA I-III.

Probably not a fit

Patients with a history of esophagogastric pathology, previous abdominal surgery, or those on medications affecting gastric emptying may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the use of gastric ultrasonography performed by trained anesthesiologists to assess gastric content in patients taking GLP-1 receptor agonists prior to scheduled surgery. The aim is to determine if this technique can help make informed clinical decisions regarding airway management and reduce the risk of aspiration pneumonia. Eligible participants include adults over 18 years who are undergoing surgery after a fasting period of 6 to 8 hours. The study will exclude individuals with certain gastrointestinal conditions or those on medications that affect gastric emptying.

Why it matters

Potential benefit: If successful, this approach could enhance patient safety by reducing the risk of aspiration pneumonia during surgery.

How similar studies have gone: While the use of gastric ultrasound in this context is relatively novel, similar studies have shown promise in improving airway management outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Adults patients ,ASA I-III, taking GLP-1 analog medications, undergoing scheduled surgery.

Exclusion Criteria:

1. \- History of esophagogastric pathology or previous abdominal surgery.
2. \- Hiatal hernia/gastroesophageal reflux disease.
3. \- Autonomic nervous system disorders.
4. \- Neurological or neuromuscular diseases.
5. \- Use of medications/drugs that affect autonomic regulation and delay gastric emptying (opioids) or potentiate it (prokinetics).
6. \- Pregnancy.
7. \- Presence of arrhythmias.

Where it's running

  • Clinica Universidad Navarra
    Madrid, Madrid, Spain
    Recruiting
  • CAUSA Salamanca
    Salamanca, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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    This study is testing if using a special camera to clear mucus from the lungs helps people with aspiration pneumonia in the emergency department feel better compared to the usual method.

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  • Assessing gastric volume and emptying in pediatric surgery patients

    This study tests if using ultrasound to measure stomach size and how quickly it empties is reliable for kids having surgery, compared to a standard test, to help keep them safe during anesthesia.

    Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT05674643

  • Esophagus and stomach movement problems and aspiration risk in children with neurologic impairment

    This trial will test prucalopride versus famotidine to see which better reduces coughing, choking, and other aspiration-associated symptoms in tube-fed children ages 5–21 with neurologic impairment.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.