Using gastric ultrasound to improve airway management in patients on GLP-1 medications

Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)

Observational Clinica Universidad de Navarra, Universidad de Navarra · NCT06666049

This study is testing if using ultrasound to check stomach contents can help doctors manage the airways of patients on GLP-1 medications before surgery to lower the risk of aspiration pneumonia.

Quick facts

Study typeObservational
Enrollment39 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorClinica Universidad de Navarra, Universidad de Navarra Academic / other
Locations2 sites (Madrid, Madrid and 1 other locations)
Trial IDNCT06666049 on ClinicalTrials.gov

What this trial studies

This observational study investigates the use of gastric ultrasonography performed by trained anesthesiologists to assess gastric content in patients taking GLP-1 receptor agonists prior to scheduled surgery. The aim is to determine if this technique can help make informed clinical decisions regarding airway management and reduce the risk of aspiration pneumonia. Eligible participants include adults over 18 years who are undergoing surgery after a fasting period of 6 to 8 hours. The study will exclude individuals with certain gastrointestinal conditions or those on medications that affect gastric emptying.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years taking GLP-1 analog medications and classified as ASA I-III.

Not a fit: Patients with a history of esophagogastric pathology, previous abdominal surgery, or those on medications affecting gastric emptying may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance patient safety by reducing the risk of aspiration pneumonia during surgery.

How similar studies have performed: While the use of gastric ultrasound in this context is relatively novel, similar studies have shown promise in improving airway management outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Adults patients ,ASA I-III, taking GLP-1 analog medications, undergoing scheduled surgery.

Exclusion Criteria:

1. \- History of esophagogastric pathology or previous abdominal surgery.
2. \- Hiatal hernia/gastroesophageal reflux disease.
3. \- Autonomic nervous system disorders.
4. \- Neurological or neuromuscular diseases.
5. \- Use of medications/drugs that affect autonomic regulation and delay gastric emptying (opioids) or potentiate it (prokinetics).
6. \- Pregnancy.
7. \- Presence of arrhythmias.

Where this trial is running

Madrid, Madrid and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aspiration PneumoniaBronchopulmonary complicationsUltrasound
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.