Using Gallium-68-DOTATOC PET/CT to Analyze Heart Inflammation in Cancer Patients
Official title: GATED-PET Heart Analysis in Patients Having a Gallium-68--DOTATOC PET/CT Exam for Oncology Indication
Run by Central Hospital, Nancy, France · NCT06467968 · Data updated 2026-11-12
This study is testing if a special imaging technique can help doctors see heart inflammation in cancer patients who are being checked for neuroendocrine tumors.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 99 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 1 site (Vandœuvre-lès-Nancy) |
| Status | Recruiting |
| Started | February 2, 2023 |
| Main results expected | February 24, 2027 |
| Study ends | May 26, 2027 |
| Registry record updated | June 25, 2026 |
| Trial ID | NCT06467968 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are scheduled for a Gallium-68-DOTATOC PET/CT exam for neuroendocrine tumor assessment.
✕Probably not a fit
Patients with a history of heart disease, severe arrhythmias, or those who cannot undergo a PET-CT scan will likely not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the use of Gallium-68-DOTATOC PET/CT imaging to assess cardiac inflammation in patients undergoing evaluation for neuroendocrine tumors. Participants will receive a Gallium-68-DOTATOC infusion followed by a PET/CT scan in GATED mode, which allows for detailed cardiac imaging. Blood samples will also be collected to measure biomarkers related to heart health. The goal is to correlate imaging findings with patient age and cardiovascular risk factors.
Why it matters
Potential benefit: If successful, this approach could enhance the understanding and management of cardiac inflammation in cancer patients, potentially leading to improved patient outcomes.
How similar studies have gone: While the use of PET imaging in oncology is well-established, the specific application of GATED mode for cardiac inflammation in this context is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Persons who have received complete information on the organization of the research and who have signed the informed consent and: * Age ≥ 18 years old. * Having read and understood the information document. * Affiliated to a social security scheme. Person for whom a 68Ga-DOTATOC PET/CT exam is requested as part of the diagnostic or pre-therapeutic assessment of a neuroendocrine tumour. Exclusion Criteria: Person with * Hypersensitivity during previous use of 68Ga-DOTATOC * Impossibility of performing a PET-CT (patient agitated, confused, etc.). * History of heart disease, * Severe arrhythmia that does not allow the PET synchronized with the ECG * Severe renal insufficiency (GFR \<30 ml/min/1.73 m2) * Treated with a somatostatin analogue. * Cushing's syndrome * Pregnant woman, likely to be or breastfeeding * Adult subject to a legal protection measure (guardianship, curators, legal safeguard) * Person of legal age unable to express their consent * Person deprived of liberty by a judicial or administrative decision * Person, subject to psychiatric care under articles L. 3212-1 and L. 3213-1
Where it's running
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Veronique Roch
Vandœuvre-lès-Nancy, France Recruiting
Study contacts
- Principal investigator: Mathieu PERRIN, MD — CHRU Nancy
- Study coordinator: VERONIQUE ROCH, MSc
- Email: v.roch@chru-nancy.fr
- Phone: 03 83 15 42 76
Similar studies
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-
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.