Using functional MRI to assess recovery in patients with optic neuritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the brain's resting-state functional MRI (fMRI) in patients diagnosed with optic neuritis. Participants will undergo a multi-parametric MRI, including an additional resting-state fMRI sequence before receiving a gadolinium contrast agent. Alongside the MRI, patients will have a consultation with an ophthalmologist, which includes visual acuity tests and optical coherence tomography. The study seeks to gather data that may help anticipate recovery outcomes for these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over 18 years of age
* Clinical suspicion of optic neuritis
* Benefiting from an MRI for exploration of optic neuritis
* Affiliate or beneficiary of a social security scheme
* Having received informed information about the study and having given their express consent to participate in the study

Exclusion Criteria:

* Contraindication to absolute or relative MRI (in particular, pregnant or breastfeeding women)
* History of amblyopia
* Any pre-existing pathology leading to a decrease in vision (e.g. retinitis pigmentosa, AMD, etc.)
* Patient benefiting from a legal protection measure

Where it's running

• Fondation A De Rothschild
  Paris, Paris, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.