Using flexible endoscopy to assist in rectal cancer surgery
Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME)
This study is testing a new way to perform surgery for rectal cancer that uses a flexible camera to help protect the anus and improve recovery for patients with tumors close to it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5 (estimated) |
| Sex | All |
| Sponsor | Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06380855 on ClinicalTrials.gov |
What this trial studies
This study explores the use of flexible endoscopy combined with transanal total mesorectal resection (taTME) to minimize anal injury during surgery for rectal cancer. The approach involves closing the distal rectum with a purse suture and making a full-layer incision of the rectal wall using a flexible colonoscope. By integrating these techniques, the study aims to enhance surgical outcomes and reduce complications associated with traditional methods. The focus is on patients with rectal adenocarcinoma located within 12 cm of the anal margin.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 80 with confirmed rectal adenocarcinoma located within 12 cm from the anal margin.
Not a fit: Patients with distant metastasis, multiple colorectal tumors, or recurrent rectal cancer are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to reduced anal injury and improved recovery for patients undergoing surgery for rectal cancer.
How similar studies have performed: While the use of flexible endoscopy in surgical procedures is established, this specific hybrid approach is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 18 and 80 years old 2. Confirmed rectal adenocarcinoma cancer pathologically 3. tumor location ≦ 12 cm from the anal margin 4. Willing and able to provide written informed consent for participation in this study Exclusion Criteria: 1. distant metastasis before surgery 2. more than one colorectal tumor at diagnosis 3. familial adenomatous polyposis 4. recurrent rectal cancer 5. undergo transanal minimally invasive surgery 6. undergo palliative treatment 7. undergo emergency surgery
Where this trial is running
Guangzhou, Guangdong
- Department of colorectal surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Liang Kang, MD. and Phd.
- Email: kangl@mail.sysu.edu.cn
- Phone: 020-38455369
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.