Using fecal microbiota transplantation to prevent recurrent urinary tract infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of fecal microbiota transplantation (FMT) as a method to prevent recurrent urinary tract infections (UTIs) in female patients. Participants will receive either FMT or a placebo to assess the effectiveness of this intervention against UTIs caused by both sensitive and ESBL-producing E. coli. The study aims to determine if altering gut microbiota can reduce the frequency of UTIs in individuals with a history of recurrent infections. Eligible participants must have experienced multiple UTIs within a specified timeframe and provide informed consent to participate.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Female subjects aged ≥18
* History of recurrent UTI: at least two episodes of UTI over the past 6 months or at least three episodes over the past year, most recent episode within the past three months
* Written informed consent

Exclusion criteria:

* Suspected non-compliance
* Diagnosis of a gastrointestinal disease
* Pregnancy
* Immunosuppression
* Any kind of permanent urinary catheter or intermittent urinary catheterization
* Any other criteria which, in the investigator's opinion, would compromise the ability of the subject to participate in the study, the subject's well-being, or the outcome of the study

Where it's running

• Meilahti Vaccine Research Center, Helsinki University Central Hospital
  Helsinki, Finland Recruiting

Study contacts

• Study coordinator: Sari Pakkanen, PhD
• Email: vti-tutkimus@hus.fi
• Phone: +358 50 4482769

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Effect of ASTARTE™ Probiotic on Recurrent Urinary Tract Infections

  This study is testing if a special probiotic can help women aged 18-40 who keep getting urinary tract infections feel better and have fewer symptoms.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.