Using eye tracking to understand social perception in children with Angelman syndrome
Use of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman Syndrome
This study is testing how children with Angelman syndrome see and understand social situations compared to healthy kids, using eye tracking technology to help find ways to measure their progress in future treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 3 Years to 17 Years |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT06737718 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on children with Angelman syndrome, a rare neurogenetic disorder characterized by severe developmental delays and specific behavioral traits. The research employs eye tracking technology to investigate social perception abnormalities in these children, aiming to identify potential biomarkers for assessing improvements in clinical trials. The study includes 40 children diagnosed with Angelman syndrome and 20 healthy control children, aged 3 to 17 years, to compare social perception capabilities. Data will be collected from patients' medical files alongside eye tracking assessments.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 3 to 17 years diagnosed with Angelman syndrome or healthy children without known neurological conditions.
Not a fit: Patients who refuse to participate in the study will not benefit from the findings.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of social perception in children with Angelman syndrome, potentially leading to improved diagnostic tools and treatment strategies.
How similar studies have performed: While eye tracking has been successfully used in autism spectrum disorder research, its application in Angelman syndrome is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 40 children with Angelman syndrome diagnosed by genetic assessment or EEG. * 20 healthy volunteer control children with no known genetic or psychiatric neurological pathology. * Aged between 3 - 17 years. * Male or female. * Holders of parental authority and minors informed and not opposed to participation in the research. Exclusion Criteria: * Refusal to participate in the study.
Where this trial is running
Paris
- Hôpital Necker-Enfants Malades — Paris, France (Recruiting)
Study contacts
- Study coordinator: Nathalie MD, PhD Boddaert
- Email: nathalie.boddaert@aphp.fr
- Phone: 0033171396530
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.