Using eye movement recordings to assess comorbidities in childhood absence epilepsy
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
This study is testing a new way to use eye movement tracking to help doctors better identify childhood absence epilepsy and related learning issues in kids.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 4 Years to 12 Years |
| Sex | All |
| Sponsor | Eysz, Inc. Industry-sponsored |
| Locations | 2 sites (Orange, California and 1 other locations) |
| Trial ID | NCT06310772 on ClinicalTrials.gov |
What this trial studies
This observational study aims to improve the identification of childhood absence epilepsy (CAE) and its associated cognitive issues by utilizing a novel system that analyzes eye movements. Current diagnostic methods are often expensive and time-consuming, leading to underdiagnosis of seizure burden and cognitive comorbidities. The Eysz system will be compared to traditional tests like EEGs and questionnaires to evaluate its effectiveness in predicting seizures and cognitive problems in children with CAE. By focusing on eye movement features, the study seeks to enable earlier diagnosis and intervention, ultimately enhancing treatment outcomes for affected children.
Who should consider this trial
Good fit: Ideal candidates include children diagnosed with childhood absence epilepsy or healthy controls fluent in English.
Not a fit: Patients with significant vision abnormalities, a history of generalized tonic-clonic seizures, or certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to quicker and more accurate diagnoses of childhood absence epilepsy, improving cognitive outcomes for affected children.
How similar studies have performed: While the use of eye movement analysis in epilepsy is a novel approach, similar studies have shown promise in improving diagnostic accuracy in other neurological conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Diagnosis of Childhood Absence Epilepsy by Treating Neurologist or a Healthy control Fluent in English Exclusion Criteria: History of subarachnoid hemorrhage, sickle cell anemia, recent cerebrovascular accident or myocardial infarction, significant cardiopulmonary disease, active asthma, known aneurysm, known moyamoya disease, or pregnancy. Known diagnosis of strabismus or amblyopia Any vision abnormalities that prevent the participant from viewing the screen clearly People who have a history of generalized tonic clonic convulsions To participate as a healthy control the participant must have no personal history of epilepsy, ADHD or other developmental disorder, no first degree relatives with the above diagnosis
Where this trial is running
Orange, California and 1 other locations
- Children's Hospital Orange County — Orange, California, United States (Recruiting)
- Wake Forest Baptist Health — Winston-Salem, North Carolina, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.