Clinical trial Recruiting at 4 sites Observational

Using eye exams and AI to help diagnose lung diseases

Official title: Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology

Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT05847894 · Data updated 2026-11-12

This study is testing if eye exams can help doctors find lung diseases earlier by using artificial intelligence to analyze the results from patients with lung problems and healthy individuals.

Quick facts

Study typeObservational
SexAll
Enrollment10000 (estimated)
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University
Academic / other
Locations4 sites (Guangzhou, Guangdong and 3 other locations)
StatusRecruiting
StartedJune 29, 2020
Main results expectedMay 2027
Study endsMay 2027
Registry record updatedAugust 12, 2026
Trial IDNCT05847894 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 18 and older with respiratory-related diseases who can undergo both ophthalmologic and pulmonary examinations.

Probably not a fit

Patients with serious underlying diseases or those unable to complete the required examinations may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather results from ophthalmologic and pulmonary examinations of patients with pulmonary diseases and control groups. By utilizing big data analysis and artificial intelligence, the study seeks to determine if eye examinations can provide new strategies for early screening of pulmonary diseases. The goal is to assist in identifying different types of pulmonary diseases and predicting their prognosis based on the collected data.

Why it matters

Potential benefit: If successful, this approach could lead to earlier and more accurate diagnoses of pulmonary diseases, improving patient outcomes.

How similar studies have gone: While the use of AI in medical diagnostics is growing, this specific approach combining ophthalmologic examinations with pulmonary disease diagnosis is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Those aged ≥18 years; or those aged \<18 years who can cooperate with the relevant examination and are accompanied and informed by a guardian;
* People with respiratory-related diseases who were to undergo pulmonary examination, or those who volunteered to participate in the trial through publicity recruitment;
* expected survival time of 3 months or more;
* Those with no previous serious underlying disease and no history of serious eye disease;
* Those who can cooperate with ophthalmologic and pulmonary-related examinations and have regular follow-up examinations;
* Those who gave informed consent to the study prior to the trial and voluntarily signed the informed consent form;
* Other conditions that can be included in the study as judged by the investigator.

Exclusion Criteria:

* Patients who are unable to complete ophthalmology or pulmonary-related examinations and regular follow-ups due to serious diseases, trauma or surgery (serious ophthalmology diseases such as extremely poor vision that cannot be fixed, ocular atrophy, severe refractive interstitial clouding that prevents fundus photography, etc.);
* People with poor compliance due to various reasons such as alcohol or drug dependence, or mental disorders;
* Those without informed consent;
* Other conditions judged by the investigator to be unsuitable for participation in the trial.

Where it's running

  • Zhongshan Ophthalmic Center, Sun Yat-sen University
    Guangzhou, Guangdong, China
    Recruiting
  • Guangzhou Kindness Health Care Center (Guangzhou Jiubang Shanxin Clinic Ltd)
    Guangzhou, Guangdong, China
    Recruiting
  • the First Affiliated Hospital of Guangzhou Medical University
    Guangzhou, Guangdong, China
    Recruiting
  • Shenzhen Third People's Hospital
    Shenzhen, Guangdong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.