Using Erector Spinae Plane Block to Reduce Pain After Spine Surgery
Effectiveness of Erector Spinae Plane Block for Percutaneous Arthrodesis of Spinal Fractures: a Randomized Controlled Trial
This study is testing if a special pain relief technique can help people who have spine surgery feel less pain and use less morphine afterward.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 86 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 1 site (Lille) |
| Trial ID | NCT06200298 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of the erector spinae plane block (ESPB) technique in reducing postoperative pain for patients undergoing percutaneous arthrodesis for spinal fractures. The study is designed as a double-blind randomized controlled trial, comparing the analgesic effects of ESPB with naropine versus a saline control. The primary objective is to demonstrate a significant reduction in morphine consumption post-surgery, with an expected decrease of 30%. This approach aims to enhance pain management and improve recovery outcomes for patients undergoing spinal surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are undergoing percutaneous arthrodesis spine surgery for fractures.
Not a fit: Patients with a history of spinal surgery, those unable to use morphine PCA, or those with preoperative neuropathic pain may not benefit from this study.
Why it matters
Potential benefit: If successful, this technique could significantly reduce postoperative pain and morphine use, leading to better recovery experiences for patients.
How similar studies have performed: Previous studies have shown promising results with the erector spinae plane block technique, indicating potential effectiveness in similar contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with percutaneous arthrodesis spine surgery for fracture 2. Insured persons 3. Age 18 years 4. Being able to receive informed information 5. Have agreed to participate in writing Exclusion Criteria: 1. Minor patient 2. Patient refusal 3. Pregnancy 4. Lack of social security coverage 5. Under guardianship or curatorship 6. Inability to express consent 7. History of spinal surgery 8. Unable to use morphine PCA 9. Contraindication to the use of local morphines and/or anesthetics 10. Contraindication to Loco-Regional Anesthesia 11. Long-term opioid patient (Level II and Level III analgesics) 12. Patient with preoperative neuropathic pain (score greater than or equal to 4 on the DN4 questionnaire or taking anti-epileptic or anti-depressant treatments for neuropathic pain)
Where this trial is running
Lille
- Hôpital Roger Salengro — Lille, France (Recruiting)
Study contacts
- Principal investigator: Cédric CIRENEI, MD — University Hospital, Lille
- Study coordinator: Cédric CIRENEI, MD
- Email: cedric.cirenei@chru-lille.fr
- Phone: 0320445962
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.