Using epidural oxycodone for pain relief after lower limb amputation
Epidural Oxycodone for Pain Management for Lower Limb Amputation: A Randomized Controlled Trial
This study tests whether using epidural oxycodone can help reduce pain, especially phantom limb pain, in people who have had a lower limb amputation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Kafrelsheikh University Academic / other |
| Locations | 1 site (Kafr Ash Shaykh, Kafrelsheikh) |
| Trial ID | NCT06276179 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of epidural oxycodone in managing pain following lower limb amputation. It focuses on addressing phantom limb pain, which can be severe and difficult to treat. The study involves administering oxycodone alongside bupivacaine to patients undergoing lower limb amputation under epidural anesthesia. The goal is to determine if this method can improve pain management outcomes in this patient population.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 who are undergoing lower limb amputation and are under epidural anesthesia.
Not a fit: Patients with hypersensitivity to opioids, severe renal impairment, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce phantom limb pain and improve recovery for patients after lower limb amputation.
How similar studies have performed: While the use of opioids for pain management is common, the specific application of epidural oxycodone for phantom limb pain is less explored, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 to 65 years. * Both sexes. * American Society of Anesthesiologists (ASA) physical status II or III. * Undergoing lower limb amputation. * Under epidural anesthesia. Exclusion Criteria: * Hypersensitivity to opioids. * Cardiac arrhythmias. * Acute asthma or other obstructive airways disease. * Severe renal impairment. * Pregnancy.
Where this trial is running
Kafr Ash Shaykh, Kafrelsheikh
- Kafrelsheikh University — Kafr Ash Shaykh, Kafrelsheikh, Egypt (Recruiting)
Study contacts
- Study coordinator: Gamal H Shams, MD
- Email: gamal.shams2@gmail.com
- Phone: 00201095927971
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.