Using endoscopic submucosal dissection for early gastrointestinal cancer treatment in the UK
Endoscopic Submucosal Dissection in the Treatment of Early Gastrointestinal Neoplasia: A UK Cohort Study to Assess Effectiveness and Safety
Portsmouth Hospitals NHS Trust · NCT03039309
This study is testing whether a special procedure called endoscopic submucosal dissection can effectively treat early gastrointestinal cancer and what the results are for patients in the UK.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Portsmouth Hospitals NHS Trust (other gov) |
| Locations | 1 site (Portsmouth) |
| Trial ID | NCT03039309 on ClinicalTrials.gov |
What this trial studies
This multicentre cohort study focuses on the application of endoscopic submucosal dissection (ESD) for treating early gastrointestinal neoplasia. Data will be collected from various centers regarding en bloc resection, curative resection, R0 resection rates, and any complications or adverse events over a two-year follow-up period. Additionally, demographic information and details about the size and location of the lesions will be documented to better understand the outcomes associated with ESD.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are undergoing endoscopic submucosal dissection for early gastrointestinal neoplasia.
Not a fit: Patients under the age of 18 or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment outcomes for patients with early gastrointestinal neoplasia by providing insights into the effectiveness and safety of endoscopic submucosal dissection.
How similar studies have performed: Other studies have shown promising results with endoscopic submucosal dissection for early gastrointestinal neoplasia, indicating that this approach is supported by prior evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or Female, aged 18 years or above undergoing endoscopic submucosal dissection * Participant is able to give informed consent for participation in the study Exclusion Criteria: * Patients under the age of 18 * Patients unable to give informed consent
Where this trial is running
Portsmouth
- Portsmputh Hospitals NHS Trust — Portsmouth, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Prof Pradeep Bhandari, MBBS, MD — Portsmouth Hospitals NHS Trust
- Study coordinator: Prof Pradeep Bhandari, MBBS, MD
- Email: pradeep.bhandari@porthosp.nhs.uk
- Phone: 02392286000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Endoscopic Submucosal Dissection