Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using endoscopic submucosal dissection for early gastrointestinal cancer treatment in the UK

Official title: Endoscopic Submucosal Dissection in the Treatment of Early Gastrointestinal Neoplasia: A UK Cohort Study to Assess Effectiveness and Safety

Run by Portsmouth Hospitals NHS Trust · NCT03039309 · Data updated 2026-11-12

This study is testing whether a special procedure called endoscopic submucosal dissection can effectively treat early gastrointestinal cancer and what the results are for patients in the UK.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorPortsmouth Hospitals NHS Trust
Government
Locations1 site (Portsmouth)
StatusRecruiting
StartedAugust 5, 2016
Main results expectedAugust 5, 2028
Study endsAugust 5, 2028
Registry record updatedSeptember 17, 2026
Trial IDNCT03039309 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are undergoing endoscopic submucosal dissection for early gastrointestinal neoplasia.

Probably not a fit

Patients under the age of 18 or those unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicentre cohort study focuses on the application of endoscopic submucosal dissection (ESD) for treating early gastrointestinal neoplasia. Data will be collected from various centers regarding en bloc resection, curative resection, R0 resection rates, and any complications or adverse events over a two-year follow-up period. Additionally, demographic information and details about the size and location of the lesions will be documented to better understand the outcomes associated with ESD.

Why it matters

Potential benefit: If successful, this study could improve treatment outcomes for patients with early gastrointestinal neoplasia by providing insights into the effectiveness and safety of endoscopic submucosal dissection.

How similar studies have gone: Other studies have shown promising results with endoscopic submucosal dissection for early gastrointestinal neoplasia, indicating that this approach is supported by prior evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or Female, aged 18 years or above undergoing endoscopic submucosal dissection
* Participant is able to give informed consent for participation in the study

Exclusion Criteria:

* Patients under the age of 18
* Patients unable to give informed consent

Where it's running

  • Portsmputh Hospitals NHS Trust
    Portsmouth, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.