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Clinical trial No longer in our active list Phase 3 Interventional Ages 18 to 65 Men only

Using EMLA cream to improve comfort during outpatient scrotal surgeries

Official title: Efficacy of EMLA Cream Assisted Loco-sedation for Office-based Andrology Procedure: A Randomized Controlled Study

Run by University of Manitoba · NCT06242977 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study tests if using EMLA cream can make outpatient scrotal surgeries more comfortable for patients compared to just using local anesthesia alone.

Quick facts

PhasePhase 3
Study typeInterventional
Ages18 Years to 65 Years
SexMen only
Enrollment72 (estimated)
SponsorUniversity of Manitoba
Academic / other
Locations1 site (Winnipeg, Manitoba)
Trial IDNCT06242977 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients scheduled for specific scrotal surgeries under local anesthesia.

Probably not a fit

Patients who require sedation or do not consent to randomization will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of EMLA cream, a topical anesthetic, in enhancing patient comfort during office-based scrotal surgeries performed under local anesthesia. The study compares the experiences of patients receiving local anesthesia alone to those receiving local anesthesia with EMLA cream. By moving these procedures from hospital settings to outpatient clinics, the trial aims to demonstrate the benefits of reduced complications, lower costs, and improved patient satisfaction. The goal is to determine if EMLA can further increase tolerability and reduce anxiety associated with these procedures.

Why it matters

Potential benefit: If successful, this approach could significantly improve patient comfort and satisfaction during outpatient scrotal surgeries.

How similar studies have gone: Previous studies have shown positive outcomes with EMLA cream in other urologic procedures, suggesting potential for success in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Adult patients undergoing hydrocelectomy, spermatocelectomy, epididymectomy, testicular biopsy, scrotal lesion or cyst excision under local anesthesia alone were included.

Exclusion Criteria:

* Patients were excluded if their procedure was to be performed with sedatives (e.g., inhaled nitrous oxide gas, oral, or IV sedation) or did not provide consent to be randomized

Where it's running

  • Men's Health Clinic Manitoba
    Winnipeg, Manitoba, Canada     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Scrotum Disease 2Local Anesthesia 6University of Manitoba 54
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.