Using EMLA cream to improve comfort during outpatient scrotal surgeries

Efficacy of EMLA Cream Assisted Loco-sedation for Office-based Andrology Procedure: A Randomized Controlled Study

Phase 3 Interventional University of Manitoba · NCT06242977

This study tests if using EMLA cream can make outpatient scrotal surgeries more comfortable for patients compared to just using local anesthesia alone.

Quick facts

PhasePhase 3
Study typeInterventional
Enrollment72 (estimated)
Ages18 Years to 65 Years
SexMale
SponsorUniversity of Manitoba Academic / other
Locations1 site (Winnipeg, Manitoba)
Trial IDNCT06242977 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of EMLA cream, a topical anesthetic, in enhancing patient comfort during office-based scrotal surgeries performed under local anesthesia. The study compares the experiences of patients receiving local anesthesia alone to those receiving local anesthesia with EMLA cream. By moving these procedures from hospital settings to outpatient clinics, the trial aims to demonstrate the benefits of reduced complications, lower costs, and improved patient satisfaction. The goal is to determine if EMLA can further increase tolerability and reduce anxiety associated with these procedures.

Who should consider this trial

Good fit: Ideal candidates for this study are adult patients scheduled for specific scrotal surgeries under local anesthesia.

Not a fit: Patients who require sedation or do not consent to randomization will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve patient comfort and satisfaction during outpatient scrotal surgeries.

How similar studies have performed: Previous studies have shown positive outcomes with EMLA cream in other urologic procedures, suggesting potential for success in this context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients undergoing hydrocelectomy, spermatocelectomy, epididymectomy, testicular biopsy, scrotal lesion or cyst excision under local anesthesia alone were included.

Exclusion Criteria:

* Patients were excluded if their procedure was to be performed with sedatives (e.g., inhaled nitrous oxide gas, oral, or IV sedation) or did not provide consent to be randomized

Where this trial is running

Winnipeg, Manitoba

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Scrotum DiseaseHydrocele MaleSpermatoceleScrotal HematoceleLocal Anesthesia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.