Using electroacupuncture to regulate immune cells in herpes zoster patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of electroacupuncture on immune cell regulation in patients with herpes zoster (HZ), a viral infection that causes pain and blistering. It will enroll 8 HZ patients and 3 healthy controls, randomly assigning patients to receive either standard medication or medication combined with electroacupuncture. The study will analyze changes in immune cells using mass cytometry before, during, and after treatment, while also assessing pain intensity and lesion healing. The goal is to determine if electroacupuncture can enhance immune response and alleviate symptoms associated with HZ.

Why it matters

Who can join: the full rules

Inclusion Criteria for HZ:

* Meets HZ diagnostic criteria;
* Female, aged between 50 and 70 years;
* Disease duration ≤7 days, with no prior antiviral, analgesic, or other treatments;
* Herpetic lesions limited to the trunk, within 1 to 3 dermatomes;
* Willing to participate in the trial and has signed the informed consent form.

Inclusion Criteria for HC:

* No history of HZ or major cardiovascular, respiratory, digestive, urinary, hematologic, endocrine, or neurological diseases;
* Age-matched female HC volunteers for the HZ group;
* Clear consciousness and ability to communicate normally;
* Fully understands the study protocol, demonstrates good compliance, and is willing to cooperate with the study;
* Has signed a written informed consent form.

Exclusion Criteria:

* Special types of herpes zoster, including ophthalmic, otic, visceral, meningeal herpes zoster, and zoster sine herpete;
* Women who are planning to conceive, pregnant, or breastfeeding;
* Patients with severe primary diseases of the circulatory, respiratory, or endocrine systems, or systemic failure;
* Patients with bleeding tendencies;
* Use of corticosteroids or immunosuppressants within the past month.

Where it's running

• The Affiliated Hangzhou First People's Hospital
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Yan Shi
• Email: tumingqi1230@163.com
• Phone: 13867439433

Similar studies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.