Using EEG to predict outcomes in patients with brain injury after cardiac arrest

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational substudy, part of the STEPCARE Trial, focuses on analyzing EEG data to predict favorable outcomes in adult patients who have experienced out-of-hospital cardiac arrest and have returned to spontaneous circulation. The study compares a new algorithm-based EEG index, the C-Trend Index, with traditional visual analysis of continuous EEG to determine which method more accurately predicts patient recovery. EEG recordings will be collected using a Brainstatus device, and the analysis will be conducted retrospectively, focusing on data collected 9-12 hours after resuscitation. The goal is to establish whether the C-Trend Index can provide at least a 10% improvement in predictive accuracy over visual analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* OHCA, with sustained ROSC
* Unconscious after ROSC
* No limitations to full life support
* Randomized to STEPCARE Trial in a participating center with Brainstatus device available

Exclusion Criteria:

* age \<18
* Previously randomized to STEPCARE
* Trauma or hemorrhage as the reasons for arrest
* Suspected or confirmed intracerebral hemorrhage
* Allergy to adhesive material
* Damaged skin at the frontal-temporal are preventing electrode attachment

Where it's running

• Helsinki University Hospital
  Helsinki, Finland Recruiting
• Kuopio University Hospital
  Kuopio, Finland Recruiting
• Tampere University Hospital
  Tampere, Finland Recruiting
• Skane University Hospital
  Lund, Sweden Recruiting

Study contacts

• Study coordinator: Johanna Hästbacka, a/c professor
• Email: johanna.hastbacka@tuni.fi
• Phone: +358415058360

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.