Using EEG in stroke units to find hidden seizures and predict epilepsy

The Value of EEG in Stroke Units

Observational Attikon Hospital · NCT07190976

This project uses routine EEG in adults hospitalized with recent ischemic or hemorrhagic stroke to see if EEG can detect hidden seizures and predict who will develop epilepsy.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorAttikon Hospital Academic / other
Locations1 site (Chaïdári, Athens)
Trial IDNCT07190976 on ClinicalTrials.gov

What this trial studies

This is an observational study enrolling adults admitted to a stroke unit after acute ischemic or hemorrhagic stroke. Participants receive routine EEG recordings within the first days after their event regardless of whether seizures are clinically suspected. Investigators will look for subclinical electroencephalographic seizures and EEG patterns that might be associated with later development of epilepsy, and will relate EEG findings to functional outcomes. The study is conducted at the Attikon University Hospital stroke unit in Athens.

Who should consider this trial

Good fit: Adults over 18 with a confirmed acute ischemic or hemorrhagic stroke who are hospitalized in the participating stroke unit within the first days after the event are ideal candidates.

Not a fit: People who are not hospitalized in the participating stroke unit, who present too late after their stroke, or who do not have a confirmed stroke are unlikely to benefit from this study's procedures or findings.

Why it matters

Potential benefit: If successful, routine early EEG could allow earlier identification of hidden seizures and patients at higher risk of developing epilepsy, enabling closer monitoring or earlier intervention to improve outcomes.

How similar studies have performed: Previous research has shown that EEG can detect post-stroke seizures and that some EEG features correlate with later epilepsy risk, but results have been mixed and prospective data remain limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: Patients over 18 years of age with confirmed acute ischemic or hemorrhagic stroke are eligible for inclusion in the study. Patients whose clinical presentation mimics that of a stroke will be included until the diagnosis of stroke is ruled out, at which point they will be excluded from the study.

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Exclusion Criteria:

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Where this trial is running

Chaïdári, Athens

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Epilepsy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.