Using EEG and ANI to Improve Recovery After Gynecological Surgery
Official title: Quality of Recovery After Electroencephalogram and Nociception Level-guided Versus Standard Anesthesia Care in Female Patients Undergoing Laparoscopic Gynecological Surgery: A Randomized Controlled Trial
Run by Gangnam Severance Hospital · NCT05936671 · Data updated 2026-11-12
This study is testing if using special brain monitoring during anesthesia can help women recover better after laparoscopic gynecological surgery compared to standard anesthesia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 19 Years and up |
| Sex | Women only |
| Enrollment | 126 (estimated) |
| Sponsor | Gangnam Severance Hospital Academic / other |
| Locations | 2 sites (Seoul, Seoul and 1 other locations) |
| Status | Recruiting |
| Started | July 13, 2023 |
| Main results expected | June 19, 2027 |
| Study ends | June 25, 2027 |
| Registry record updated | July 23, 2026 |
| Trial ID | NCT05936671 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult women scheduled for laparoscopic gynecological surgeries such as hysterectomy or myomectomy.
✕Probably not a fit
Patients with irregular cardiac rhythms, implanted pacemakers, or those on specific medications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of electroencephalogram (EEG) and Analgesia Nociception Index (ANI)-guided anesthesia in enhancing recovery quality following laparoscopic gynecological surgery. Participants will be randomly assigned to either the EEG-and-ANI-guided anesthesia group or a standard care group. The primary outcome will be assessed using the Quality of Recovery (QoR-15) score on the first postoperative day, while secondary outcomes will include various measures such as remifentanil consumption and postoperative pain scores. The study aims to determine if guided anesthesia can lead to better recovery outcomes compared to traditional methods.
Why it matters
Potential benefit: If successful, this approach could lead to improved recovery experiences for patients undergoing laparoscopic gynecological surgeries.
How similar studies have gone: While the use of EEG and ANI in anesthesia is gaining interest, this specific approach has not been widely tested, making it a novel investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adult female patients who are scheduled to undergo laparoscopic gynecological surgery. 1. Total laparoscopic hysterectomy with/without salpingo-oophorectomy 2. Laparoscopic myomectomy 3. Laparoscope-guided salpingo-oophorectomy 4. Laparoscope-guided ovarian cystectomy 5. Laparoscope-guided enucleation of ovarian cyst Exclusion Criteria: 1. Patients with nonregular sinus cardiac rhythm 2. Patients with implanted pacemakers 3. Patients on antimuscarinic agents, α2-adrenergic agonists, β1-adrenergic antagonists, antiarrhythmic agents 4. pregnant or breastfeeding women 5. Patients who are unable to communicate
Where it's running
-
GangnamSeverance Hospital
Seoul, Seoul, South Korea Recruiting -
Gangnam Severance Hospital
Seoul, Seoul, South Korea Not yet recruiting
Study contacts
- Principal investigator: Dong Woo Han, MD,PhD — Gangnam Severance Hospital
- Study coordinator: Sun-Kyung Park, MD,PhD
- Email: mayskpark@gmail.com
- Phone: 821024505924
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.