Clinical trial Recruiting at 1 site Interventional Ages 1 Day to 45 Days

Using ECG to guide umbilical vein catheter placement in neonates

Official title: Umbilical Vessel Catheterization Under ECG Monitoring and Guidance

Run by Stanford University · NCT03898596 · Data updated 2026-11-12

This study is testing whether using ECG monitoring can help doctors place umbilical venous catheters more accurately in newborns with acute lymphoblastic leukemia.

Quick facts

Study typeInterventional
Ages1 Day to 45 Days
SexAll
Enrollment150 (estimated)
SponsorStanford University
Academic / other
Locations1 site (Palo Alto, California)
StatusRecruiting
StartedAugust 25, 2020
Main results expectedDecember 2025
Study endsDecember 2025
Registry record updatedMay 1, 2025
Trial IDNCT03898596 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are neonate pediatric patients weighing between 2 to 6 kg who require or currently have a UVC.

Probably not a fit

Patients who are clinically unstable or do not have parental consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on improving the placement of umbilical venous catheters (UVC) in neonates by utilizing electrocardiogram (ECG) monitoring for guidance. The traditional methods of catheter placement often lack precision and can lead to misplacement in critical areas, posing risks to infants. By employing ECG tracings, the study aims to provide a non-invasive and continuous monitoring approach to ensure accurate catheter placement. This could enhance the safety and effectiveness of UVC procedures in pediatric patients with acute lymphoblastic leukemia (ALL).

Why it matters

Potential benefit: If successful, this approach could significantly reduce the risks associated with UVC misplacement in critically ill neonates.

How similar studies have gone: While the use of ECG for catheter placement is a novel approach, similar studies have shown promise in improving procedural accuracy in other medical contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Neonate pediatric patient
* 2 - 6kg
* Require or currently have UVC

Exclusion Criteria:

* Participants who do not consent or have parental consent
* Patients who are clinically unstable

Where it's running

  • Lucille Packard Children's Hospital
    Palo Alto, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.