Using ECG to guide umbilical vein catheter placement in neonates
Official title: Umbilical Vessel Catheterization Under ECG Monitoring and Guidance
Run by Stanford University · NCT03898596 · Data updated 2026-11-12
This study is testing whether using ECG monitoring can help doctors place umbilical venous catheters more accurately in newborns with acute lymphoblastic leukemia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 1 Day to 45 Days |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Stanford University Academic / other |
| Locations | 1 site (Palo Alto, California) |
| Status | Recruiting |
| Started | August 25, 2020 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | May 1, 2025 |
| Trial ID | NCT03898596 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are neonate pediatric patients weighing between 2 to 6 kg who require or currently have a UVC.
✕Probably not a fit
Patients who are clinically unstable or do not have parental consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on improving the placement of umbilical venous catheters (UVC) in neonates by utilizing electrocardiogram (ECG) monitoring for guidance. The traditional methods of catheter placement often lack precision and can lead to misplacement in critical areas, posing risks to infants. By employing ECG tracings, the study aims to provide a non-invasive and continuous monitoring approach to ensure accurate catheter placement. This could enhance the safety and effectiveness of UVC procedures in pediatric patients with acute lymphoblastic leukemia (ALL).
Why it matters
Potential benefit: If successful, this approach could significantly reduce the risks associated with UVC misplacement in critically ill neonates.
How similar studies have gone: While the use of ECG for catheter placement is a novel approach, similar studies have shown promise in improving procedural accuracy in other medical contexts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Neonate pediatric patient * 2 - 6kg * Require or currently have UVC Exclusion Criteria: * Participants who do not consent or have parental consent * Patients who are clinically unstable
Where it's running
-
Lucille Packard Children's Hospital
Palo Alto, California, United States Recruiting
Study contacts
- Study coordinator: Chynna Villanueva, BS, RN
- Email: chynnav@stanford.edu
- Phone: 6504986346
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.