Using ECG to guide umbilical vein catheter placement in neonates

Umbilical Vessel Catheterization Under ECG Monitoring and Guidance

Not applicable Interventional Stanford University · NCT03898596

This study is testing whether using ECG monitoring can help doctors place umbilical venous catheters more accurately in newborns with acute lymphoblastic leukemia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages1 Day to 45 Days
SexAll
SponsorStanford University Academic / other
Locations1 site (Palo Alto, California)
Trial IDNCT03898596 on ClinicalTrials.gov

What this trial studies

This study focuses on improving the placement of umbilical venous catheters (UVC) in neonates by utilizing electrocardiogram (ECG) monitoring for guidance. The traditional methods of catheter placement often lack precision and can lead to misplacement in critical areas, posing risks to infants. By employing ECG tracings, the study aims to provide a non-invasive and continuous monitoring approach to ensure accurate catheter placement. This could enhance the safety and effectiveness of UVC procedures in pediatric patients with acute lymphoblastic leukemia (ALL).

Who should consider this trial

Good fit: Ideal candidates for this study are neonate pediatric patients weighing between 2 to 6 kg who require or currently have a UVC.

Not a fit: Patients who are clinically unstable or do not have parental consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the risks associated with UVC misplacement in critically ill neonates.

How similar studies have performed: While the use of ECG for catheter placement is a novel approach, similar studies have shown promise in improving procedural accuracy in other medical contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Neonate pediatric patient
* 2 - 6kg
* Require or currently have UVC

Exclusion Criteria:

* Participants who do not consent or have parental consent
* Patients who are clinically unstable

Where this trial is running

Palo Alto, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pediatric ALLNeonatesElectrocardiogramUmbilical Vein Catheterization
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.