Using Dynamic Airway CT to Diagnose Tracheomalacia in Children
Dynamic Airway CT is Diagnostic for Tracheomalacia in Children
This study is testing if a new type of CT scan can help doctors diagnose tracheomalacia in children more accurately and safely than the current method.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Sponsor | NYU Langone Health Academic / other |
| Drugs / interventions | radiation |
| Locations | 2 sites (New York, New York and 1 other locations) |
| Trial ID | NCT06028646 on ClinicalTrials.gov |
What this trial studies
This pilot interventional study evaluates the effectiveness of Dynamic Airway Computed Tomography (DA-CT) in diagnosing tracheomalacia in children aged 0-18 who have undergone flexible bronchoscopy. The study aims to assess the diagnostic accuracy, image quality, and radiation exposure of DA-CT as a noninvasive alternative to the traditional method of flexible bronchoscopy. The findings will inform the design of a larger study to better estimate the diagnostic potential of DA-CT for this condition.
Who should consider this trial
Good fit: Ideal candidates are children aged 0-18 who have had a clinically indicated flexible bronchoscopy.
Not a fit: Patients who are pregnant, breastfeeding, unable to undergo CT scanning without sedation, or have a tracheostomy will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a safer, noninvasive diagnostic option for children with tracheomalacia.
How similar studies have performed: While this approach is innovative, it is not yet widely tested, making it a novel investigation in the field.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants 0-18 years old, with * Clinically indicated flexible bronchoscopy has been performed Exclusion Criteria: * Pregnancy or breastfeeding * Unable to undergo CT scanning without sedation * Patients with tracheostomy
Where this trial is running
New York, New York and 1 other locations
- Fink Children's Ambulatory Center/Hassenfeld Children's Center — New York, New York, United States (Recruiting)
- Tisch Hospital — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Eleanor Muise, MD — NYU Langone Health
- Study coordinator: Soumia Hammouda
- Email: Soumia.Hammouda@nyulangone.org
- Phone: 347-204-3293
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.