Using Doxycycline to treat Type 2 Diabetes
Doxycycline in Combination With Sitagliptin on the Glycemic and Cardiac Indices in Patients With Type 2 Diabetes Mellitus
This study is testing if the antibiotic Doxycycline can help people over 40 with newly diagnosed Type 2 Diabetes improve their blood sugar control when combined with another diabetes medication.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta) |
| Trial ID | NCT06329882 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of Doxycycline in patients with newly diagnosed Type 2 Diabetes Mellitus (T2DM). The study aims to assess how Doxycycline, alongside Sitagliptin, can influence insulin resistance and improve glycemic control in individuals over 40 years old. Participants will be monitored for changes in blood sugar levels and other metabolic parameters. The trial is designed to gather data on the safety and efficacy of this treatment approach.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals over 40 years old who have recently been diagnosed with Type 2 Diabetes and have an HbA1c level greater than 6.5.
Not a fit: Patients with chronic kidney disease, hepatic disorders, mental health issues, or those who are pregnant or lactating may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could improve blood sugar control and metabolic health in patients with Type 2 Diabetes.
How similar studies have performed: While the specific combination of Doxycycline and Sitagliptin is novel, previous studies have explored the role of antibiotics in metabolic diseases, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female sex more than 40 years old Newly diagnosed type II diabetes. HbA1c more than 6.5 Exclusion Criteria: * Patient with chronic kidney disease, hepatic disorders, mental and psychiatric disorders, pregnancy, and lactation
Where this trial is running
Tanta
- Tanta Unuversity — Tanta, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.