Using Doppler endoscopic probe to diagnose gastrointestinal lesions

Role of Doppler Endoscopic Probe in the Diagnosis of Subepithelial Gastrointestinal Lesions.

Not applicable Interventional Karolinska University Hospital · NCT05983406

This study is testing whether a special Doppler endoscopic probe can help doctors better diagnose certain types of growths in the upper digestive tract.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorKarolinska University Hospital Academic / other
Locations1 site (Stockholm)
Trial IDNCT05983406 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of a Doppler endoscopic probe in diagnosing subepithelial lesions (SELs) in the upper gastrointestinal tract. SELs are often detected during routine endoscopies, but traditional methods like endoscopic ultrasound (EUS) have limitations in providing definitive diagnoses. The study aims to improve diagnostic accuracy and management of these lesions by utilizing Doppler technology, which may enhance the characterization of vascular involvement. Participants will undergo Doppler investigations to assess the potential benefits of this approach compared to standard methods.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with detected subepithelial lesions in the gastrointestinal tract.

Not a fit: Patients on anticoagulation therapy that cannot be discontinued, those with liver cirrhosis and coagulopathy, or individuals with malignancy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses of subepithelial gastrointestinal lesions, improving patient management and outcomes.

How similar studies have performed: While traditional methods like EUS have been widely used, the application of Doppler technology in this context is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Presence of subepithelial lesion on the GI tract.

Exclusion Criteria:

* Anticoagulation therapy that cannot be discontinued
* Liver cirrhosis with coagulopathy or varices
* Malignancy

Where this trial is running

Stockholm

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Subepithelial Tumors of the Upper Gastrointestinal TractDoppler, EUS, SEL
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.