Using dogs to help diagnose high-risk prostate cancer
Contribution of Canine Detection in the Diagnostic Strategy of High-risk Prostate Cancer
Assistance Publique - Hôpitaux de Paris · NCT05558735
This study is testing whether trained dogs can help find high-risk prostate cancer in adult patients by using their urine samples alongside traditional tests like MRIs and biopsies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 183 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | Assistance Publique - Hôpitaux de Paris (other) |
| Locations | 1 site (Paris) |
| Trial ID | NCT05558735 on ClinicalTrials.gov |
What this trial studies
This observational study aims to validate the effectiveness of canine detection in identifying high-risk prostate cancers by comparing it to traditional diagnostic methods like MRI and biopsies. Adult patients suspected of prostate cancer will provide urine samples, which will be analyzed alongside their MRI results and biopsy outcomes. The study will take place at Bichat-Claude Bernard and Henri Mondor hospitals in France, focusing on patients who meet specific diagnostic criteria. The goal is to integrate canine detection into the current diagnostic strategy for prostate cancer.
Who should consider this trial
Good fit: Ideal candidates are adult males over 18 years old who are suspected of having prostate cancer and require urine collection, PSA testing, MRI, and biopsies as part of their care.
Not a fit: Patients who do not speak French, are unable to provide informed consent, or have severe health conditions that prevent participation will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance the accuracy of prostate cancer diagnosis and potentially reduce the need for invasive procedures.
How similar studies have performed: While the use of canine detection in medical diagnostics is novel, similar studies in other fields have shown promising results, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
"Inclusion criteria : * Older than 18 years old * Requiring the realization of a collection of urine from the framework of their care * Requiring a PSA blood test, prostate MRI and prostate biopsies in the framework of their care Exclusion criteria : * Absence of signed informed consent * People who do not speak French * Persons whose general condition does not allow to participate in the study * Protected populations: under guardianship or under curatorship * Persons deprived of their liberty by a judicial or administrative decision * Persons receiving care psychiatric * Absence of affiliation to a pension scheme social Security"
Where this trial is running
Paris
- Hopital Bichat - Claude-Bernard — Paris, France (RECRUITING)
Study contacts
- Principal investigator: Hermieu Jean-François, Surgeon — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Hermieu Jean-François, Surgeon
- Email: jean-françois.hermieu@aphp.fr
- Phone: 0140257103
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: High-risk Prostate Cancer, prostate cancer, canine detection, the dog's sense of smell