Using digital technology to treat postpartum depression in low-resource settings

Sensing Technologies for Maternal Depression Treatment in Low-Resource Settings

Not applicable Interventional George Washington University · NCT06253676

This study tests if a digital mental health program can help new mothers in Nepal who are struggling with postpartum depression feel better compared to regular support.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages15 Years to 45 Years
SexFemale
SponsorGeorge Washington University Academic / other
Locations1 site (Kathmandu)
Trial IDNCT06253676 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of the StandStrong intervention, a digital mental health program designed for postpartum-depressed mothers in Nepal. The intervention utilizes passive sensing technology to collect data on mothers' health and behavior, which is then analyzed and used by non-specialist providers to tailor support. By comparing this approach to standard non-specialist mental health interventions, the study aims to determine the acceptability and clinical efficacy of integrating digital tools into mental health care. The trial addresses the significant issue of untreated postpartum depression in low- and middle-income countries.

Who should consider this trial

Good fit: Ideal candidates for this study are mothers aged 15-39 with infants within their first 1000 days of life who have a PHQ-9 score of 8 or higher.

Not a fit: Patients with a PHQ-9 score below 8 or those presenting acute medical needs or psychotic symptoms may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve mental health outcomes for postpartum mothers in low-resource settings.

How similar studies have performed: Previous studies have shown mixed results for non-specialist interventions, but the integration of digital technology in this context is a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Mother Age: 15-39 years
* Infant Age: Within 1st 1000 days of life
* Mother PHQ-9 Score: 8+
* Access to a technology charging modality within home
* Will remain in the study area for a minimum of 6 months after enrollment

Exclusion Criteria:

* Mother PHQ-9 Score: Less Than 8
* Different permanent residences of mother and infant at time of recruitment
* Acute medical need or hospitalization of mother or infant at time of recruitment
* Presentation of psychotic symptoms (as indicated by the psychosis module of the locally validated Community Informant Detection Tool) at time of recruitment

Where this trial is running

Kathmandu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post Partum DepressionLow- and Middle-Income CountryMental HealthTask-Sharing Intervention / Non-Specialist InterventionmHealth | Digital Health
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.