Using Dexmedetomidine or Tramadol with Paracetamol to Reduce Bladder Discomfort After Surgery
Official title: The Effect of Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder Discomfort: A Randomized, Triple-Blind Clinical Trial
Run by Al-Azhar University · NCT06274333 · Data updated 2026-11-12
This study is testing whether adding Dexmedetomidine or Tramadol to Paracetamol can help reduce bladder discomfort after surgery for people aged 20 to 50.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 20 Years to 50 Years |
| Sex | Men only |
| Enrollment | 60 (estimated) |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | February 28, 2024 |
| Main results expected | August 30, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | January 6, 2026 |
| Trial ID | NCT06274333 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 20 to 50 years who are classified as ASA I or II and are scheduled for percutaneous nephrolithotomy.
✕Probably not a fit
Patients with a history of psychotic illnesses, current opioid users, or those with bladder obstruction or overactive bladder may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of adding Dexmedetomidine or Tramadol to Paracetamol in reducing catheter-related bladder discomfort (CRBD) in patients undergoing percutaneous nephrolithotripsy (PCNL). The study aims to evaluate how these medications can alleviate postoperative pain and discomfort associated with urinary catheters. Participants will receive either Dexmedetomidine or Tramadol alongside Paracetamol during their surgical procedure. The trial focuses on patients aged 20 to 50 years with specific health criteria to ensure safety and efficacy.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative bladder discomfort for patients undergoing urinary procedures.
How similar studies have gone: Other studies have shown promising results with similar approaches to managing postoperative pain and discomfort, suggesting potential for success in this trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age from 20 - 50 years * ASA (The American Society of Anesthesiologists) I or II, * undergo percutaneous nephrolithotomy (PCNL) Exclusion Criteria: * Patients with history of psychotic illnesses * Opioid users * Bladder obstruction, * Benign prostatic hyperplasia * Overactive bladder (OAB) defined as frequency \_3 times at night or \_8 times within 24 hours.
Where it's running
-
Neveen Kohaf
Cairo, Cairo Governorate, Egypt Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.